Personal profile

Research interests

Katharine’s overall goal is to develop improved mechanical circulatory support devices for patients with severe heart failure. To do this Katharine works in three main areas:

  1. Design optimisation of ventricular assist devices (VADs) and other types of artificial heart. Katharine mainly uses CFD and numerical models of blood damage, but also works on validation, using optical methods, and improvement of CFD methods.
  2. Investigation of the interaction between mechanical circulatory support and the native cardiovascular system. This involves studying the effects of altered blood flow on blood, for example the trauma induced on the blood cells and proteins, as well as on the blood vessels.
  3. Development of new techniques for studying the above, for example Ultrasound Imaging Velocimetry, a novel method for using ultrasound to measure blood velocity.

Katharine is also interested in other biofluid mechanics, and related bioengineering, problems and has recently worked on mock artery flow rigs, altering the flow in vascular bioreactors and measuring flow changes after nephrectomy.

Katharine’s research has led to consultancy work for companies including Calon Cardio-Technology Ltd and CorWave SAS, and has been used by the US Food and Drug Administration.

Fingerprint Fingerprint is based on mining the text of the person's scientific documents to create an index of weighted terms, which defines the key subjects of each individual researcher.

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Heart-Assist Devices Medicine & Life Sciences
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Velocity measurement Engineering & Materials Science

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Projects 2015 2016

Research Output 2004 2017

Blood residence times in Ventricular Assist Devices

Masri, Z., Molteni, A., Yousef, H., Low, K., Porter, H. & Fraser, K. 24 Jun 2017 1 p.

Research output: Contribution to conferencePoster

damage
residence time
blood
shear stress
dye

Experimental and Numerical Analysis of Dye Washout in Ventricular Assist Devices

Molteni, A., Yousef, H., Low, K., Porter, H. & Fraser, K. 1 Apr 2017 In : Journal of Heart and Lung Transplantation. 36, 4, p. S324 997

Research output: Contribution to journalMeeting abstract

Heart-Assist Devices
Coloring Agents
Hydrodynamics
Convection
Glycerol

Leukocyte deformation in cardiac assist devices

Fraser, K. & Pieper, I. L. 10 Apr 2017 p. 442 445 p.

Research output: Contribution to conferencePaper

Leukocytes
Equipment and Supplies
Heart-Assist Devices
Infection
Surgeons
Heart-Assist Devices
Shear stress
Blood
Hydrodynamics
Strain rate
Shear stress
Blood
Fluid dynamics
Strain rate
Numerical models

Datasets

Dataset for "Ultrasound Imaging Velocimetry with interleaved images for improved pulsatile arterial flow measurements: a new correction method, experimental and in vivo validation"

Fraser, K. (Creator), Poelma, C. (Creator), Zhou, Z. (Creator), Bazigou, E. (Creator), Tang, M. (Creator), Weinberg, P. (Creator), University of Bath, 2016

Dataset