Projects per year
Personal profile
Research interests
My research is broadly concerned with developing economically efficient scale-up systems for cell therapy manufacturing. I design and compare different bioreactor configurations for the culture and manufacturing of cell and cell-derived products. Currently, I focus on production of red blood cells from an immortalized blood progenitor cell line (Bristol Erythroid Lineage- Adult; BELA cells) and will also be working towards developing systems for production of stem cell-derived therapeutic extracellular vesicles.
Willing to supervise doctoral students
I welcome enquiries from potential PhD students in the areas of regenerative medicine, in particular bioprocess engineering.
Education/Academic qualification
Biomedical Engineering, Doctor of Philosophy, An evaluation of tailored magnetic nanoparticles in the induction of stem cell differentiation, Keele University
Keywords
- Bioreactors
- Regenerative medicine
- Extracellular vesicles
- Blood Manufacturing
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
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Advancing bioactive materials and medical devices for health innovation and regenerative tissue engineering through European collaboration
Perge, L. (PI), Leese, H. (CoI), Moise, S. (CoI), Mazancova, N. (Researcher) & Harrison, J. (Researcher)
1/01/26 → 31/12/26
Project: Central government, health and local authorities
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EPSRC IAA - Fluidised bed bioreactors for manufacture of therapeutic mammalian suspension cells (Extension)
Moise, S. (PI), Fraser, K. (CoI) & Phillips, D. (Researcher)
Engineering and Physical Sciences Research Council
20/01/26 → 31/03/26
Project: Research council
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EPSRC IAA - Fluidised bed bioreactors for manufacture of therapeutic mammalian suspension cells
Moise, S. (PI), Fraser, K. (CoI) & Phillips, D. (Researcher)
Engineering and Physical Sciences Research Council
17/08/25 → 4/05/26
Project: Research council
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EPSRC IAA - Fluidised bed bioreactors for large-scale manufacture of mammalian single cell suspension-derived therapeutics
Phillips, D. (PI) & Moise, S. (CoI)
Engineering and Physical Sciences Research Council
14/10/24 → 27/04/25
Project: Research council
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Manufacturing in Hospital: BioMed 4.0
Leese, H. (PI), Castro Dominguez, B. (CoI), Flynn, J. (CoI), Gill, R. (CoI), Martinez Hernandez, U. (CoI), Moise, S. (CoI) & Wilson, P. (CoI)
Engineering and Physical Sciences Research Council
2/11/21 → 29/08/25
Project: Research council
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Determining the biodegradation of functionalised cellulose esters
Entwistle, K., Moise, S., Guler Gencer, F., Smart, K. A., Crow, M. & Chuck, C. J., 1 Jan 2026, In: Faraday Discussions. 262, p. 414-431 18 p.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (SciVal) -
Effect of dynamic culture conditions on the production of an erythroid progenitor cell line within fluidised bed bioreactors
Phillips, D., Ellis, M., Frayne, J. & Moise, S., 31 Jan 2026, In: Biochemical Engineering Journal. 225, 109936.Research output: Contribution to journal › Article › peer-review
Open Access -
Flow Orientation as a Critical Parameter in Nanoscale Membrane Filtration for Optimising Small Extracellular Vesicle Isolation
Nujhat, S., Leese, H. S., Strickland, M. A., Di Lorenzo, M. & Moise, S., 27 Mar 2026, (E-pub ahead of print) In: Nanoscale Advances.Research output: Contribution to journal › Article › peer-review
Open Access -
Characterizing a novel adult erythroid cell line for red blood cell manufacture
Phillips, D., Ellis, M. J., Frayne, J. & Moise, S., 6 May 2025, (E-pub ahead of print) In: Bioengineering and Translational Medicine. e70026.Research output: Contribution to journal › Article › peer-review
Open Access2 Link opens in a new tab Citations (SciVal) -
Potato protein isolate hydrogels as potential scaffolds for bone tissue engineering
Zhu, M., De Bank, P., Ellis, M. & Moise, S., 19 May 2025.Research output: Contribution to conference › Poster
Open AccessFile81 Downloads (Pure)
Datasets
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Dataset for "Assessing the immunosuppressive activity of alginate-encapsulated mesenchymal stromal cells on splenocytes"
Moise, S. (Creator), University of Bath, 21 Jun 2022
DOI: 10.15125/BATH-01069
Dataset
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Dataset for "Characterising a novel adult erythroid cell line for red blood cell manufacture"
Phillips, D. (Creator), Moise, S. (Supervisor), Ellis, M. (Supervisor) & Frayne, J. (Contributor), University of Bath, 6 May 2025
DOI: 10.15125/BATH-01456
Dataset