Sulphydryl-dependent reactions of D-penicillamine: Pharmacokinetics and effects on monocyte function in rheumatoid arthritis.

Abstract

The project consisted of two major sections:- (i) A high performance liquid chromatography assay to determine total D-penicillamine in human plasma was developed and modified. The final system comprised two columns together with a switching valve, coupled with an electrochemical detector fitted with a sulphydryl-specific amalgamated gold electrode. The resultant chromatography was rapid, exhibited high sensitivity (

Date of Award	1985
Original language	English
Awarding Institution	University of Bath