Modelling of the clinical 9.2 GHz MEA Applicator

Abstract

This thesis describes the analysis, via computational and experimental modelling techniques, of temperature distributions produced by a 9.2 GHz microwave applicator. This applicator is currently used for a clinical treatment known as Microwave Endometrial Ablation (MEA). The computational modelling uses commercial software packages, based on the Finite Element Method, together with bespoke computer programs to perform combined electromagnetic and thermal analyses of the applicator. Results from these analyses are then validated by the experimental measurement of temperatures, in phantom tissue, produced by heating from the applicator. Computational and experimental modelling is then used to investigate the extent to which the applicator was able to cause denaturation in biological materials. Finally, a new variant of the applicator – the Flat-tipped Applicator - is proposed for treating other medical conditions. As well as being modelled computationally and experimentally, the histological effects of using the Flat-tipped Applicator to heat excised human skin tissue are investigated.

Date of Award	27 Jun 2001
Original language	English
Awarding Institution	University of Bath
Supervisor	N J Cronin (Supervisor)