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Showing results for cancer as a concept
2011

Multicentre evaluation of intraoperative molecular analysis of sentinel lymph nodes in breast carcinoma

Snook, K. L., Layer, G. T., Jackson, P. A., De Vries, C. S., Shousha, S., Sinnett, H. D., Nigar, E., Singhal, H., Chia, Y., Cunnick, G. & Kissin, M. W., Apr 2011, In : British Journal of Surgery. 98, 4, p. 527-535 9 p.

Research output: Contribution to journalArticle

74 Citations (Scopus)

Novel clues on the specific association of Streptococcus gallolyticus subsp gallolyticus with colorectal cancer

Boleij, A., Muytjens, C. M. J., Bukhari, S. I., Cayet, N., Glaser, P., Hermans, P. W. M., Swinkels, D. W., Bolhuis, A. & Tjalsma, H., 15 Apr 2011, In : Journal of Infectious Diseases. 203, 8, p. 1101-1109 9 p.

Research output: Contribution to journalArticle

103 Citations (Scopus)

Sequential DNA methylation changes are associated with DNMT3B overexpression in colorectal neoplastic progression

Ibrahim, A. E. K., Arends, M. J., Silva, A-L., Wyllie, A. H., Greger, L., Ito, Y., Vowler, S. L., Huang, T. H-M., Tavaré, S., Murrell, A. & Brenton, J. D., Apr 2011, In : Gut. 60, 4, p. 499-508 10 p.

Research output: Contribution to journalArticle

80 Citations (Scopus)

Small molecule inhibitors that discriminate between protein arginine N-methyltransferases PRMT1 and CARM1

Dowden, J., Pike, R. A., Parry, R. V., Hong, W., Muhsen, U. A. & Ward, S. G., 26 Oct 2011, In : Organic and Biomolecular Chemistry. 9, 22, p. 7814-7821 8 p.

Research output: Contribution to journalArticle

29 Citations (Scopus)

Steroid sulfatase: a pivotal player in estrogen synthesis and metabolism

Purohit, A., Woo, L. W. L. & Potter, B. V. L., 4 Jul 2011, In : Molecular and Cellular Endocrinology. 340, 2, p. 154-160

Research output: Contribution to journalArticle

Open Access
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49 Citations (Scopus)
150 Downloads (Pure)

Synthesis and spectral characteristics of gold nanoparticles labelled with fluorescein sodium

Elfeky, S. A. & Al-Sherbini, A. A., Dec 2011, In : Current Nanoscience. 7, 6, p. 1028-1033 6 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2010

{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo

Abramkin, S. A., Jungwirth, U., Valiahdi, S. M., Dworak, C., Habala, L., Meelich, K., Berger, W., Jakupec, M. A., Hartinger, C. G., Nazarov, A. A., Galanski, M. & Keppler, B. K., 28 Oct 2010, In : Journal of Medicinal Chemistry. 53, 20, p. 7356-64 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate

Falasca, M., Chiozzotto, D., Godage, H. Y., Mazzoletti, M., Riley, A. M., Previdi, S., Potter, B. V. L., Broggini, M. & Maffucci, T., 5 Jan 2010, In : British Journal of Cancer. 102, 1, p. 104-114

Research output: Contribution to journalArticle

43 Citations (Scopus)

Bicyclic derivatives of the potent dual aromatase-steroid sulfatase inhibitor 2-bromo-4-{ (4-cyanophenyl)(4H-1,2,4-triazol-4-yl)amino methyl}phenylsul famate: synthesis, SAR, crystal structure, and in vitro and in vivo activities

Wood, P. M., Woo, L. W. L., Labrosse, J-R., Thomas, M. P., Mahon, M. F., Chander, S. K., Purohit, A., Reed, M. J. & Potter, B. V. L., 3 Sep 2010, In : ChemMedChem. 5, 9, p. 1577-1593

Research output: Contribution to journalArticle

20 Citations (Scopus)

Chemical Basis for the Selectivity of the von Hippel Lindau Tumor Suppressor pVHL for Prolyl-Hydroxylated HIF-1 alpha

Illingworth, C. J. R., Loenarz, C., Schofield, C. J. & Domene Nunez, C., 1 Aug 2010, In : Biochemistry. 49, 32, p. 6936-6944 9 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Class III β-tubulin expression and in vitro resistance to microtubule targeting agents

Stengel, C., Newman, S. P., Leese, M. P., Potter, B. V. L., Reed, M. J. & Purohit, A., Jan 2010, In : British Journal of Cancer. 102, 2, p. 316-324

Research output: Contribution to journalArticle

104 Citations (Scopus)

Crystal structure of an Aurora-A mutant that mimics Aurora-B bound to MLN8054: insights into selectivity and drug design

Dodson, C., Kosmopoulou, M., Richards, M., Atrash, B., Bavetsias, V., Blagg, J. & Bayliss, R., 1 Apr 2010, In : Biochemical Journal. 427, 1, p. 19-28 9 p.

Research output: Contribution to journalArticle

55 Citations (Scopus)

Evaluation of allelic expression of imprinted genes in adult human blood

Frost, J. M., Monk, D., Stojilkovic-Mikic, T., Woodfine, K., Chitty, L. S., Murrell, A., Stanier, P. & Moore, G. E., 2010, In : PLoS ONE. 5, 10, e13556.

Research output: Contribution to journalArticle

Open Access
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25 Citations (Scopus)
120 Downloads (Pure)

Evaluation of clinical interventions made by pharmacists in chemotherapy preparation

Knez, L., Laaksonen, R. & Duggan, C., Dec 2010, In : Radiology and Oncology. 44, 4, p. 249-256 8 p.

Research output: Contribution to journalArticle

13 Citations (Scopus)

Highly potent first examples of dual aromatase-steroid sulfatase inhibitors based on a biphenyl template

Woo, L. . W. L., Jackson, T., Putey, A., Cozier, G., Leonard, P., Acharya, K. R., Chander, S. K., Purohit, A., Reed, M. J. & Potter, B. V. L., 11 Mar 2010, In : Journal of Medicinal Chemistry. 53, 5, p. 2155-2170

Research output: Contribution to journalArticle

69 Citations (Scopus)

Human RASSF7 regulates the microtubule cytoskeleton and is required for spindle formation, Aurora B activation and chromosomal congression during mitosis

Recino, A., Sherwood, V., Flaxman, A., Cooper, WN., Latif, F., Ward, A. & Chalmers, A. D., 1 Sep 2010, In : Biochemical Journal. 430, 2, p. 207-213 7 p.

Research output: Contribution to journalArticle

Open Access
21 Citations (Scopus)
73 Downloads (Pure)

Intracellular protein binding patterns of the anticancer ruthenium drugs KP1019 and KP1339

Heffeter, P., Böck, K., Atil, B., Reza Hoda, M. A., Körner, W., Bartel, C., Jungwirth, U., Keppler, B. K., Micksche, M., Berger, W. & Koellensperger, G., Jun 2010, In : Journal of Biological Inorganic Chemistry. 15, 5, p. 737-48 12 p.

Research output: Contribution to journalArticle

115 Citations (Scopus)

Jade and the journalists: media coverage of a young British celebrity dying of cancer

Walter, T., Sep 2010, In : Social Science and Medicine. 71, 5, p. 853-860 8 p.

Research output: Contribution to journalArticle

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19 Citations (Scopus)
153 Downloads (Pure)

Modulation of P-glycoprotein activity by the substituted quinoxalinone compound QA3 in adriamycin-resistant K562/A02 cells

Sun, L. R., Zhong, J. L., Cui, S. X., Li, X., Ward, S. G., Shi, Y. Q., Zhang, X. F., Cheng, Y. N., Gao, J. J. & Qu, X. J., 2010, In : Pharmacological Reports. 62, 2, p. 333-342 10 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Mortality in psoriatic arthritis: a single-center study from the UK

Buckley, C., Cavill, C., Taylor, G., Kay, H., Waldron, N., Korendowych, E. & McHugh, N. J., Oct 2010, In : Journal of Rheumatology. 37, 10, p. 2141-2144 4 p.

Research output: Contribution to journalArticle

48 Citations (Scopus)

Structural insights into the binding of vascular endothelial growth factor-B by VEGFR-1(D2): recognition and specificity

Iyer, S., Darley, P. I. & Acharya, K. R., 30 Jul 2010, In : Journal of Biological Chemistry. 285, 31, p. 23779-23789 11 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

Synthesis and biological activity of Δ-5,6-norcantharimides: Importance of the 5,6-bridge

Thaqi, A., Scott, J. L., Gilbert, J., Sakoff, J. A. & McCluskey, A., May 2010, In : European Journal of Medicinal Chemistry. 45, 5, p. 1717-1723

Research output: Contribution to journalArticle

34 Citations (Scopus)

The experiences of young oral cancer patients in Scotland; Symptom recognition and delays in seeking professional help

Grant, L., Silver, K., Bauld, L. & Warnakulasuriya, S., May 2010, In : British Dental Journal. 208, 10, p. 465-471 7 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

The integration of healing into conventional cancer care in the UK

Lorenc, A., Peace, B., Vaghela, C. & Robinson, N., Nov 2010, In : Complementary Therapies in Clinical Practice. 16, 4, p. 222-8 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

The N-terminal RASSF family: a new group of Ras-association-domain-containing proteins, with emerging links to cancer formation

Sherwood, V., Recino, A., Jeffries, A., Ward, A. & Chalmers, A. D., 2010, In : Biochemical Journal. 425, 2, p. 303-311 9 p.

Research output: Contribution to journalReview article

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66 Citations (Scopus)
141 Downloads (Pure)