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Showing results for cancer as a concept
2012
13 Citations (Scopus)

Cancer survival through lifestyle change (CASTLE): a pilot study of weight loss

Harris, M. N., Swift, D. L., Myers, V. H., Earnest, C. P., Johannsen, N. M., Champagne, C. M., Parker, B. D., Levy, E., Cash, K. C. & Church, T. S., 2012, In : International Journal of Behavioral Medicine.

Research output: Contribution to journalArticle

Life Style
Weight Loss
Telephone
Breast Neoplasms
Survival
6 Citations (Scopus)

Colorectal cancer incidence on the General Practice Research Database

Charlton, R., Snowball, J., Bloomfield, K. & De Vries, C., 2012, In : Pharmacoepidemiology and Drug Safety. 21, 7, p. 775-783

Research output: Contribution to journalArticle

General Practice
Colorectal Neoplasms
Databases
Incidence
Research
5 Citations (Scopus)

Current management of dermatomyositis

Vermaak, E. & McHugh, N., 1 Apr 2012, In : International Journal of Clinical Rheumatology. 7, 2, p. 197-215 19 p.

Research output: Contribution to journalArticle

Dermatomyositis
Myositis
Muscle Weakness
Therapeutics
Autoantibodies
22 Citations (Scopus)

Decoding GnRH neurohormone pulse frequency by convergent signalling modules.

Tsaneva-Atanasova, K., Mina, P., Caunt, C. J., Armstrong, S. P. & McArdle, C. A., 7 Jan 2012, In : Journal of the Royal Society, Interface. 9, 66, p. 170-182 13 p.

Research output: Contribution to journalArticle

Gonadotropin-Releasing Hormone
Neurotransmitter Agents
Decoding
Transcription factors
Chemical activation
74 Citations (Scopus)

Il2rg gene-targeted severe combined immunodeficiency pigs

Suzuki, S., Iwamoto, M., Saito, Y., Fuchimoto, D., Sembon, S., Suzuki, M., Mikawa, S., Hashimoto, M., Aoki, Y., Najima, Y., Takagi, S., Suzuki, N., Suzuki, E., Kubo, M., Mimuro, J., Kashiwakura, Y., Madoiwa, S., Sakata, Y., Perry, A. C. F., Ishikawa, F. & 1 others, Onishi, A., 14 Jun 2012, In : Cell Stem Cell. 10, 6, p. 753-758 6 p.

Research output: Contribution to journalArticle

Severe Combined Immunodeficiency
Swine
Genes
Interleukin Receptor Common gamma Subunit
Heterologous Transplantation
21 Citations (Scopus)

Incidence and drug treatment of emotional distress after cancer diagnosis: a matched primary care case-control study

Desplenter, F., Bond, C., Watson, M., Burton, C., Murchie, P., Lee, A. J., Lefevre, K., Simoens, S. & Laekeman, G., 23 Oct 2012, In : British Journal of Cancer. 107, 9, p. 1644-1651 8 p.

Research output: Contribution to journalArticle

Open Access
Case-Control Studies
Primary Health Care
Incidence
Pharmaceutical Preparations
Neoplasms
6 Citations (Scopus)
103 Downloads (Pure)

Novel cis-regulatory modules control expression of the Hairy and Enhancer of Split-1 (HES1) transcription factor in myoblasts

Jeziorska, D. M., Koentges, G. & Vance, K. W., 17 Feb 2012, In : The Journal of biological chemistry. 287, 8, p. 5687-97 11 p.

Research output: Contribution to journalArticle

Open Access
File
Myoblasts
Tail
Transcription Factors
Genes
DNA sequences
29 Citations (Scopus)

Protein flexibility is key to cisplatin crosslinking in calmodulin

Li, H., Wells, S. A., Jimenez-Roldan, J. E., Römer, R. A., Zhao, Y., Sadler, P. J. & O'Connor, P. B., Sep 2012, In : Protein Science. 21, 9, p. 1269-1279 11 p.

Research output: Contribution to journalArticle

Calmodulin
Crosslinking
Cisplatin
Methionine
Cyclotrons
3 Citations (Scopus)

SMAD4-dependent polysome RNA recruitment in human pancreatic cancer cells

Thornley, J. A., Trask, H. W., Ringelberg, C. S., Ridley, C. J. A., Wang, S., Sal-Lari, R. C., Moore, J. H., Korc, M. & Tomlinson, C. R., 1 Oct 2012, In : Molecular Carcinogenesis. 51, 10, p. 771-782

Research output: Contribution to journalArticle

Polyribosomes
Pancreatic Neoplasms
RNA
Genes
Cytoplasm
2011
6 Citations (Scopus)

A motion-compensated cone-beam CT using electrical impedance tomography imaging

Pengpan, T., Smith, N. D., Qiu, W., Yao, A., Mitchell, C. N. & Soleimani, M., Jan 2011, In : Physiological Measurement. 32, 1, p. 19-34

Research output: Contribution to journalArticle

Acoustic impedance
Cone-Beam Computed Tomography
Electric Impedance
Tomography
Cones
242 Citations (Scopus)

Anticancer activity of metal complexes: involvement of redox processes

Jungwirth, U., Kowol, C. R., Keppler, B. K., Hartinger, C. G., Berger, W. & Heffeter, P., 15 Aug 2011, In : Antioxidants & Redox Signaling. 15, 4, p. 1085-127 43 p.

Research output: Contribution to journalReview article

Coordination Complexes
Oxidation-Reduction
Metals
Homeostasis
Copper
39 Citations (Scopus)

Aromatase and dual aromatase-steroid sulfatase inhibitors from the letrozole and vorozole templates

Wood, P. M., Woo, L. W. L., Thomas, M. P., Mahon, M. F., Purohit, A. & Potter, B. V. L., 1 Aug 2011, In : ChemMedChem. 6, 8, p. 1423-1438

Research output: Contribution to journalArticle

letrozole
vorozole
Steryl-Sulfatase
Sulfatases
Aromatase

Bacterial bile acid modification and potential pharmaceutical applications

Jones, B. V., 20 Oct 2011, In : Journal of Applied Therapeutic Research. 8, 3, p. 94-100 7 p.

Research output: Contribution to journalReview article

Bile Acids and Salts
choloylglycine hydrolase
Pharmaceutical Preparations
Microbiota
Metabolic Diseases
19 Citations (Scopus)

Birt Hogg-Dube Syndrome-Associated FLCN Mutations Disrupt Protein Stability

Nahorski, M. S., Reiman, A., Lim, D. H. K., Nookala, R. K., Seabra, L., Lu, X. H., Fenton, J., Boora, U., Nordenskjold, M., Latif, F., Hurst, L. D. & Maher, E. R., Aug 2011, In : Human Mutation. 32, 8, p. 921-929 9 p.

Research output: Contribution to journalArticle

Birt-Hogg-Dube Syndrome
Estrone
Protein Stability
Sequence Deletion
Mutation

Chiral inversion of NSAID-CoA esters by human ∝-methylacyl-CoA racemase

Woodman, T. J., Wood, P. J., Thompson, A. S., Hutchings, T. J., Jiao, P., Steel, G. R., Threadgill, M. D. & Lloyd, M. D., 2011.

Research output: Contribution to conferenceOther

Racemases and Epimerases
Non-Steroidal Anti-Inflammatory Agents
Coenzyme A
Baths
Esters
2 Citations (Scopus)

Cloning, expression and purification of the CCN family of proteins in Escherichia coli

Holbourn, K. P. & Acharya, K. R., 22 Apr 2011, In : Biochemical and Biophysical Research Communications. 407, 4, p. 837-841 5 p.

Research output: Contribution to journalArticle

CCN Intercellular Signaling Proteins
Cloning
Escherichia coli
Purification
Organism Cloning
11 Citations (Scopus)
200 Downloads (Pure)

Design, synthesis and antiproliferative activity of urocanic-chalcone hybrid derivatives

Ciupa, A., Griffiths, N. J., Light, S. K., Wood, P. J. & Caggiano, L., 1 Oct 2011, In : MedChemComm. 2, 10, p. 1011-1015 5 p.

Research output: Contribution to journalArticle

Open Access
File
Chalcone
Cells
Derivatives
Cell Line
Inhibitory Concentration 50
39 Citations (Scopus)
118 Downloads (Pure)

Development of steroid sulfatase inhibitors

Woo, L. W. L., Purohit, A. & Potter, B. V. L., 4 Jul 2011, In : Molecular and Cellular Endocrinology. 340, 2, p. 175-185

Research output: Contribution to journalArticle

Open Access
File
Steryl-Sulfatase
Steroids
Aromatase Inhibitors
Sulfates
Hydrolysis
26 Citations (Scopus)

Ena drives invasive macrophage migration in Drosophila embryos

Tucker, P. K., Evans, I. R. & Wood, W., Jan 2011, In : Disease Models & Mechanisms. 4, 1, p. 126-134 9 p.

Research output: Contribution to journalArticle

Hemocytes
Macrophages
Fibroblasts
Drosophila
Embryonic Structures
39 Citations (Scopus)
83 Downloads (Pure)

Functional ESCRT machinery is required for constitutive recycling of claudin-1 and maintenance of polarity in vertebrate epithelial cells

Dukes, J. D., Fish, L., Richardson, J. D., Blaikley, E., Burns, S., Caunt, C. J., Chalmers, A. D. & Whitley, P., 1 Sep 2011, In : Molecular Biology of the Cell. 22, 17, p. 3192-3205 14 p.

Research output: Contribution to journalArticle

Open Access
Endosomal Sorting Complexes Required for Transport
Claudin-1
Recycling
Vertebrates
Epithelial Cells
25 Citations (Scopus)

Hybrid dual aromatase-steroid sulfatase inhibitors with exquisite picomolar inhibitory activity

Woo, L. W. L., Bubert, C., Purohit, A. & Potter, B. V. L., Mar 2011, In : ACS Medicinal Chemistry Letters. 2, 3, p. 243-247

Research output: Contribution to journalArticle

Steryl-Sulfatase
Sulfatases
Aromatase Inhibitors
Aromatase
Inhibitory Concentration 50
18 Citations (Scopus)
100 Downloads (Pure)

Increased levels of noisy splicing in cancers, but not for oncogene-derived transcripts

Chen, L., Tovar-Corona, J. M. & Urrutia, A. O., 15 Nov 2011, In : Human Molecular Genetics. 20, 22, p. 4422-4429 8 p.

Research output: Contribution to journalArticle

File
Oncogenes
Nonsense Codon
Alternative Splicing
Neoplasms
Tumor Suppressor Genes
59 Citations (Scopus)

Inhibition of neutrophil infiltration into A549 lung tumors in vitro and in vivo using a CXCR2-specific antagonist is associated with reduced tumor growth

Tazzyman, S., Barry, S. T., Ashton, S., Wood, P., Blakey, D., Lewis, C. E. & Murdoch, C., 15 Aug 2011, In : International Journal of Cancer. 129, 4, p. 847-858 12 p.

Research output: Contribution to journalArticle

Neutrophil Infiltration
Lung
Growth
Neoplasms
Neutrophils
34 Citations (Scopus)

Insufficiency of BUBR1, a mitotic spindle checkpoint regulator, causes impaired ciliogenesis in vertebrates

Miyamoto, T., Porazinski, S., Wang, H., Borovina, A., Ciruna, B., Shimizu, A., Kajii, T., Kikuchi, A., Furutani-Seiki, M. & Matsuura, S., 15 May 2011, In : Human Molecular Genetics. 20, 10, p. 2058-2070 13 p.

Research output: Contribution to journalArticle

M Phase Cell Cycle Checkpoints
Vertebrates
Chromatids
Dandy-Walker Syndrome
Anaphase-Promoting Complex-Cyclosome
55 Citations (Scopus)

Molecular mechanisms of genomic imprinting and clinical implications for cancer

Uribe-Lewis, S., Woodfine, K., Stojic, L. & Murrell, A., 2011, In : Expert Reviews in Molecular Medicine. 13, e2.

Research output: Contribution to journalArticle

Genomic Imprinting
Epigenomics
Neoplasms
Genes
Gene Expression