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Showing results for cancer as a concept
2013
20 Citations (Scopus)

Induced DNA demethylation can reshape chromatin topology at the IGF2-H19 locus

Ito, Y., Nativio, R. & Murrell, A., 1 May 2013, In : Nucleic Acids Research. 41, 10, p. 5290-302 13 p.

Research output: Contribution to journalArticle

Somatomedins
Chromatin
DNA
Epigenomics
Choriocarcinoma
9 Citations (Scopus)

Influence of extracellular pH on the cytotoxicity, cellular accumulation, and DNA interaction of novel pH-sensitive 2-aminoalcoholatoplatinum(II) complexes

Valiahdi, S. M., Egger, A. E., Miklos, W., Jungwirth, U., Meelich, K., Nock, P., Berger, W., Hartinger, C. G., Galanski, M., Jakupec, M. A. & Keppler, B. K., Feb 2013, In : Journal of Biological Inorganic Chemistry. 18, 2, p. 249-60 12 p.

Research output: Contribution to journalArticle

Cytotoxicity
Tumors
DNA
Platinum
Cells
17 Citations (Scopus)

Interaction with Shc prevents aberrant Erk activation in the absence of extracellular stimuli

Suen, K. M., Lin, C-C., George, R., Melo, F. A., Biggs, E. R., Ahmed, Z., Drake, M. N., Arur, S., Arold, S. T. & Ladbury, J. E., May 2013, In : Nature Structural and Molecular Biology. 20, 5, p. 620-627 8 p.

Research output: Contribution to journalArticle

Shc Signaling Adaptor Proteins
Phosphotransferases
Receptor Protein-Tyrosine Kinases
Intercellular Signaling Peptides and Proteins
Homeostasis
30 Citations (Scopus)
84 Downloads (Pure)

Intra-tumor heterogeneity: lessons from microbial evolution and clinical implications

de Bruin, E. C., Taylor, T. B. & Swanton, C., 2013, In : Genome Medicine. 5, 11, p. 101-112 11 p., 5.

Research output: Contribution to journalArticle

Open Access
File
Neoplasms
Population
Mutation Rate
Drug Resistance
Longitudinal Studies

Introduction to Cancer Biology

Hejmadi, M., 2013, 2 ed. Denmark: Ventus Publishing. 48 p.

Research output: Book/ReportBook

Neoplasms
5 Citations (Scopus)

In vitro treatment of carcinoma cell lines with pancreatic (pro)enzymes suppresses the EMT programme and promotes cell differentiation

Perán, M., Marchal, J. A., García, M. A., Kenyon, J. & Tosh, D., 1 Jul 2013, In : Cellular Oncology. 36, 4, p. 289-301

Research output: Contribution to journalArticle

Epithelial-Mesenchymal Transition
Cell Differentiation
Differentiation Antigens
Carcinoma
Cell Line
85 Citations (Scopus)
120 Downloads (Pure)

MHC class I–associated phosphopeptides are the targets of memory-like immunity in Leukemia

Cobbold, M., De La Pena, H., Norris, A., Polefrone, J. M., Qian, J., English, A. M., Cummings, K. L., Penny, S., Turner, J. E., Cottine, J., Abelin, J. G., Malaker, S. A., Zarling, A. L., Huang, H-W., Goodyear, O., Freeman, S. D., Shabanowitz, J., Pratt, G., Craddock, C., Williams, M. E. & 2 others, Hunt, D. F. & Engelhard, V. H., 18 Sep 2013, In : Science Translational Medicine. 5, 203, 203ra125.

Research output: Contribution to journalArticle

File
Phosphopeptides
Immunity
Leukemia
T-Lymphocytes
Neoplasms
25 Citations (Scopus)

Mortality in systemic sclerosis-a single centre study from the UK

Strickland, G., Pauling, J., Cavill, C., Shaddick, G. & McHugh, N., Oct 2013, In : Clinical Rheumatology. 32, 10, p. 1533-1539 7 p.

Research output: Contribution to journalArticle

Systemic Scleroderma
Mortality
Confidence Intervals
Survival
Cause of Death
23 Citations (Scopus)

Re-engineering of the duocarmycin structural architecture enables bioprecursor development targeting CYP1A1 and CYP2W1 for biological activity

Sheldrake, H. M., Travica, S., Johansson, I., Loadman, P. M., Sutherland, M., Elsalem, L., Illingworth, N., Cresswell, A. J., Reuillon, T., Shnyder, S. D., Mkrtchian, S., Searcey, M., Ingelman-Sundberg, M., Patterson, L. H. & Pors, K., 8 Aug 2013, In : Journal of Medicinal Chemistry. 56, 15, p. 6273-6277 5 p.

Research output: Contribution to journalArticle

Open Access
Cytochrome P-450 CYP1A1
Libraries
Neoplasms
cyclopropapyrroloindole
2 Citations (Scopus)

Resources allocations in healthcare for cancer: A case study using generalised additive mixed models

Musio, M., Sauleau, E-A. & Augustin, N., 2013, In : Geospatial Health. 7, 1, p. 83-89 7 p.

Research output: Contribution to journalArticle

Resource Allocation
resource allocation
health care
cancer
Delivery of Health Care
21 Citations (Scopus)
98 Downloads (Pure)

SCAR/WAVE-mediated processing of engulfed apoptotic corpses is essential for effective macrophage migration in Drosophila

Evans, I., Ghai, P., Urbančič, V., Tan, K. L. & Wood, W., May 2013, In : Cell Death and Differentiation. 20, 5, p. 709-720 12 p.

Research output: Contribution to journalArticle

Open Access
File
Cadaver
Drosophila
Macrophages
Pseudopodia
Phagocytosis
35 Citations (Scopus)
118 Downloads (Pure)

Searching for prostate cancer stem cells: markers and methods

Sharpe, B., Beresford, M., Bowen, R., Mitchard, J. & Chalmers, A. D., Oct 2013, In : Stem Cell Reviews and Reports. 9, 5, p. 721-730

Research output: Contribution to journalArticle

Open Access
File
Neoplastic Stem Cells
Prostatic Neoplasms
Colony-Forming Units Assay
Neoplasms
Transgenic Mice
10 Citations (Scopus)

STX2171, a 17β-hydroxysteroid dehydrogenase type 3 inhibitor, is efficacious in vivo in a novel hormone-dependent prostate cancer model

Day, J. M., Foster, P. A., Tutill, H. J., Schmidlin, F., Sharland, C. M., Hargrave, J. D., Vicker, N., Potter, B. V. L., Reed, M. J. & Purohit, A., Feb 2013, In : Endocrine-Related Cancer. 20, 1, p. 53-64 12 p.

Research output: Contribution to journalArticle

Androstenedione
Prostatic Neoplasms
Testosterone
Hormones
Testosterone Propionate
30 Citations (Scopus)

Synergistic anticancer activity of arsenic trioxide with erlotinib is based on inhibition of EGFR-mediated DNA double-strand break repair

Kryeziu, K., Jungwirth, U., Hoda, M. A., Ferk, F., Knasmüller, S., Karnthaler-Benbakka, C., Kowol, C. R., Berger, W. & Heffeter, P., Jun 2013, In : Molecular Cancer Therapeutics. 12, 6, p. 1073-84 12 p.

Research output: Contribution to journalArticle

Double-Stranded DNA Breaks
Epidermal Growth Factor Receptor
Neoplasms
Phosphorylation
Erlotinib Hydrochloride
19 Citations (Scopus)

Synthesis and antiproliferative activity of some 3-(pyrid-2-yl)-pyrazolines

Ciupa, A., De Bank, P. A., Mahon, M. F., Wood, P. J. & Caggiano, L., 1 Jun 2013, In : MedChemComm. 4, 6, p. 956-961 6 p.

Research output: Contribution to journalArticle

Lead compounds
Cells
X Ray Crystallography
Tubulin
Tumor Cell Line
25 Citations (Scopus)

Truncated and helix-constrained peptides with high affinity and specificity for the cFos coiled-coil of AP-1

Rao, T., Ruiz-Gómez, G., Hill, T. A., Hoang, H. N., Fairlie, D. P. & Mason, J. M., 2013, In : PLoS ONE. 8, 3, p. e59415

Research output: Contribution to journalArticle

Transcription Factor AP-1
peptides
Peptides
proteins
epitopes
41 Citations (Scopus)

α-Methylacyl-CoA racemase (AMACR): Metabolic enzyme, drug metabolizer and cancer marker P504S

Lloyd, M. D., Jevglevskis, M., Lee, G. L., Wood, P. J., Threadgill, M. D. & Woodman, T. J., Apr 2013, In : Progress in Lipid Research. 52, 2, p. 220-230 11 p.

Research output: Contribution to journalArticle

Acyl Coenzyme A
Peroxisome Proliferator-Activated Receptors
Proton transfer
Oncology
Ibuprofen
2012
3 Citations (Scopus)

A microwave surface applicator for tissue coagulation: Technical characteristics and performances

Lepers, B., Clegg, P., Cronin, N. & Wieland, I., 2012, In : Journal of Medical Devices: Transactions of the ASME. 6, 1, 014502.

Research output: Contribution to journalArticle

Applicators
Microwaves
Coagulation
Tissue
Liver
63 Citations (Scopus)

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

Licchesi, J. D. F., Mieszczanek, J., Mevissen, T. E. T., Rutherford, T. J., Akutsu, M., Virdee, S., El Oualid, F., Chin, J. W., Ovaa, H., Bienz, M. & Komander, D., 2012, In : Nature Structural and Molecular Biology. 19, 1, p. 62-71 10 p.

Research output: Contribution to journalArticle

Ankyrin Repeat
Ubiquitin
Catalytic Domain
Ankyrins
Biological Phenomena
28 Citations (Scopus)

Anticancer activity of methyl-substituted oxaliplatin analogs

Jungwirth, U., Xanthos, D. N., Gojo, J., Bytzek, A. K., Körner, W., Heffeter, P., Abramkin, S. A., Jakupec, M. A., Hartinger, C. G., Windberger, U., Galanski, M., Keppler, B. K. & Berger, W., May 2012, In : Molecular Pharmacology. 81, 5, p. 719-28 10 p.

Research output: Contribution to journalArticle

oxaliplatin
Stereoisomerism
Hyperalgesia
Pharmaceutical Preparations
Weight Loss
10 Citations (Scopus)

A randomised controlled trial of a cognitive behavioural intervention for men who have hot flushes following prostate cancer treatment (MANCAN): trial protocol

Yousaf, O., Stefanopoulou, E., Grunfeld, E. A. & Hunter, M. S., 11 Jun 2012, In : BMC Cancer. 12, p. 1-7 7 p., 230.

Research output: Contribution to journalArticle

Open Access
Clinical Protocols
Sweat
Prostatic Neoplasms
Randomized Controlled Trials
Cognitive Therapy
8 Citations (Scopus)
76 Downloads (Pure)

A simple, highly visual in vivo screen for anaplastic lymphoma kinase inhibitors

Rodrigues, F. S. L. M., Yang, X., Nikaido, M., Liu, Q. & Kelsh, R. N., 21 Dec 2012, In : ACS Chemical Biology. 7, 12, p. 1968-1974 7 p.

Research output: Contribution to journalArticle

Open Access
File
Assays
Zebrafish
anaplastic lymphoma kinase
Automation
Neuroblastoma
1 Citation (Scopus)
100 Downloads (Pure)

A strategy to improve selectivity and targeting to epithelial-derived cancer cells

Liu, K., Hearne, K., Mrsny, A., Staka, C. & Mrsny, R. J., 10 Dec 2012, In : Journal of Controlled Release. 164, 2, p. 205-212 8 p.

Research output: Contribution to journalArticle

Open Access
File
Occludin
Neoplasms
Epithelial-Mesenchymal Transition
Gene Expression
Peptides
10 Citations (Scopus)
101 Downloads (Pure)

Asymmetrical N4,N9-Diacyl Spermines: SAR Studies of Nonviral Lipopolyamine Vectors for Efficient siRNA Delivery with Silencing of EGFP Reporter Gene

Blagbrough, I. S., Metwally, A. A. & Ghonaim, H. M., 2 Jul 2012, In : Molecular Pharmaceutics. 9, 7, p. 1853-1861 9 p.

Research output: Contribution to journalArticle

Open Access
File
Spermine
Reporter Genes
Small Interfering RNA
Fluorescein
Cell Line
22 Citations (Scopus)
Barrett Esophagus
Metaplasia
Esophagus
Epithelium
Esophageal Diseases