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Showing results for cancer as a concept
2017
90 Downloads (Pure)

Deformable boundary EIT for breast cancer imaging

Hu, J. & Soleimani, M., 9 Jan 2017, In : Biomedical Physics & Engineering Express . 3, 1, 015004.

Research output: Contribution to journalArticle

Open Access
File
Electric Impedance
Tomography
Breast Neoplasms
Electrodes
Breast
4 Citations (Scopus)

Depletion of somatic mutations in splicing-associated sequences in cancer genomes

Hurst, L. & Batada, N. N., 7 Nov 2017, In : Genome Biology. 18, 1, 12 p., 213.

Research output: Contribution to journalArticle

Open Access
somatic mutation
mutation
cancer
genome
Genome
10 Citations (Scopus)
158 Downloads (Pure)
Open Access
File
T-cells
Exercise
T-Lymphocytes
Neoplasms
Immune system
51 Citations (Scopus)
71 Downloads (Pure)

Do patients have worse outcomes in heart failure than in cancer? A primary care-based cohort study with 10-year follow-up in Scotland

Mamas, M. A., Sperrin, M., Watson, M. C., Coutts, A., Wilde, K., Burton, C., Kadam, U. T., Kwok, C. S., Clark, A. B., Murchie, P., Buchan, I., Hannaford, P. C. & Myint, P. K., 14 Sep 2017, In : European Journal of Heart Failure. 19, 9, p. 1095-1104 10 p.

Research output: Contribution to journalArticle

Open Access
File
Scotland
Primary Health Care
Cohort Studies
Heart Failure
Survival
9 Citations (Scopus)
132 Downloads (Pure)

Downsizing proto-oncogene cFos to short helix-constrained peptides that bind Jun

Baxter, D., Perry, S., Hill, T., Kok, W., Zaccai, N., Brady, L., Fairlie, D. & Mason, J., 17 Aug 2017, In : ACS Chemical Biology. 12, 8, p. 2051-2061 11 p.

Research output: Contribution to journalArticle

Open Access
File
Proto-Oncogenes
Peptides
Cell-Penetrating Peptides
Circular dichroism spectroscopy
Nuclear Localization Signals
900 Citations (Scopus)

Estimates and 25-year trends of the global burden of disease attributable to ambient air pollution: an analysis of data from the Global Burden of Diseases Study 2015

Cohen, A. J., Brauer, M., Burnett, R., Anderson, H. R., Frostad, J., Estep, K., Balakrishnan, K., Brunekreef, B., Dandona, L., Dandona, R., Feigin, V., Freedman, G., Hubbell, B., Jobling, A., Kan, H., Knibbs, L., Liu, Y., Martin, R., Morawska, L., Pope, C. A. & 9 others, Shin, H., Straif, K., Shaddick, G., Thomas, M., van Dingenen, R., van Donkelaar, A., Vos, T., Murray, C. J. L. & Forouzanfar, M. H., 13 May 2017, In : Lancet. 389, 10082, p. 1907-1918 12 p.

Research output: Contribution to journalArticle

Open Access
Air Pollution
Quality-Adjusted Life Years
Uncertainty
Mortality
Ozone
22 Downloads (Pure)

High-Throughput Screening to identify novel inhibitors of human α-methylacyl-CoA racemase 1A (AMACR; P504S)

Petrova, Y., Mattan, H., Lee, G. L., Jevglevskis, M., Woodman, T. & Lloyd, M., 21 Apr 2017.

Research output: Contribution to conferencePoster

File
Libraries
Prostatic Neoplasms
Pharmaceutical Preparations
Acyl Coenzyme A
Ibuprofen
3 Citations (Scopus)

How the probability of presentation to a primary care clinician correlates with cancer survival rates: a European survey using vignettes

Harris, M., Frey, P., Esteva, M., Gašparović Babić, S., Marzo-Castillejo, M., Petek, D., Petek Ster, M. & Thulesius, H., 2 Jan 2017, In : Scandinavian Journal of Primary Health Care. 35, 1, p. 27-34 8 p.

Research output: Contribution to journalArticle

Open Access
Primary Care Physicians
Primary Health Care
Survival Rate
Neoplasms
Survival
13 Citations (Scopus)

Interventional laser surgery for oral potentially malignant disorders – a longitudinal patient cohort study

Thomson, P. J., Goodson, M. L., Cocks, K. & Turner, J. E., Mar 2017, In : International Journal of Oral & Maxillofacial surgery. 46, 3, p. 337-342

Research output: Contribution to journalArticle

Laser Therapy
Cohort Studies
Squamous Cell Carcinoma
Early Diagnosis
Leukoplakia
242 Citations (Scopus)
110 Downloads (Pure)

Neuropathic pain

Colloca, L., Ludman, T., Bouhassira, D., Baron, R., Dickenson, A. H., Yarnitsky, D., Freeman, R., Truini, A., Attal, N., Finnerup, N. B., Eccleston, C., Kalso, E., Bennett, D. L., Dworkin, R. H. & Raja, S. N., 16 Feb 2017, In : Nature Reviews Disease Primers. 3, 17002.

Research output: Contribution to journalArticle

Open Access
File
Neuralgia
Drug Prescriptions
Pain
Unmyelinated Nerve Fibers
Incidence
5 Citations (Scopus)
72 Downloads (Pure)

Non-steroidal anti-inflammatory drugs (NSAIDs) for cancer-related pain in children and adolescents

Cooper, T. E., Heathcote, L. C., Anderson, B., Grégoire, M-C., Ljungman, G. & Eccleston, C., 2017, In : The Cochrane Database of Systematic Reviews. 7, 24 p., CD012563.

Research output: Contribution to journalArticle

Open Access
File
Anti-Inflammatory Agents
Pain
Pharmaceutical Preparations
Pain Management
Neoplasms

Quantitative proteomics for molecular diagnostics of public health: the quest for biomarkers of infectious disease

Rice, J., Kasprzyk-Hordern, B. & Lubben, A., 2017, Testing the waters 2017, Wastewater-based epidemiology: current applications and future perspectives, 3rd international conference.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Molecular Pathology
Proteomics
Communicable Diseases
Public Health
Biomarkers
11 Citations (Scopus)

Robust long-read native DNA sequencing using the ONT CsgG Nanopore system

Carter, J-M. & Hussain, S., 2017, In : Wellcome Open Research. 2, 23.

Research output: Contribution to journalArticle

Open Access
Nanopores
DNA Sequence Analysis
Technology
DNA
Throughput
2 Citations (Scopus)
114 Downloads (Pure)

Semiconductor technology in protein kinase research and drug discovery: sensing a revolution

Bhalla, N., Di Lorenzo, M., Estrela, P. & Pula, G., Feb 2017, In : Drug Discovery Today. 22, 2, p. 204-209 6 p.

Research output: Contribution to journalArticle

Open Access
File
Semiconductors
Drug Discovery
Protein Kinase Inhibitors
Protein Kinases
Cell Physiological Phenomena
11 Citations (Scopus)
136 Downloads (Pure)

Structural evidence of quercetin multi-target bioactivity: A reverse virtual screening strategy

Carvalho, D., Paulino, M., Polticelli, F., Arredondo, F., Williams, R. J. & Abin-Carriquiry, J. A., 19 Jun 2017, In : European Journal of Pharmaceutical Sciences. 106, p. 393-403 11 p.

Research output: Contribution to journalArticle

Open Access
File
Quercetin
Proteins
Phosphatidylinositol 3-Kinase
Poly(ADP-ribose) Polymerases
Xanthine Oxidase
2 Citations (Scopus)
46 Downloads (Pure)

The effect of medications which cause inflammation of the gastro-oesophageal tract on cancer risk: a nested case-control study of routine Scottish data

Busby, J., Murchie, P., Murray, L., Iversen, L., Lee, A. J., Spence, A., Watson, M. C. & Cardwell, C. R., 23 Feb 2017, In : International Journal of Cancer. 140, 8, p. 1828-1835 8 p.

Research output: Contribution to journalArticle

Open Access
File
Esophageal Neoplasms
Case-Control Studies
Diphosphonates
Spironolactone
Inflammation
41 Citations (Scopus)

The EuroMyositis registry: an international collaborative tool to facilitate myositis research

Lilleker, J. B., Vencovsky, J., Wang, G., Wedderburn, L. R., Diederichsen, L. P., Schmidt, J., Oakley, P., Benveniste, O., Danieli, M. G., Danko, K., Thuy, N. T. P., Vazquez-Del Mercado, M., Andersson, H., De Paepe, B., deBleecker, J. L., Maurer, B., McCann, L. J., Pipitone, N., McHugh, N., Betteridge, Z. E. & 8 others, New, P., Cooper, R. G., Ollier, W. E., Lamb, J. A., Krogh, N. S., Lundberg, I. E., Chinoy, H. & all EuroMyositis contributors, 11 Dec 2017, In : Annals of the Rheumatic Diseases. 77, 1, p. 30-39 10 p.

Research output: Contribution to journalArticle

Open Access
Myositis
Registries
Pulmonary diseases
Dermatomyositis
Research

The potential yield of active play in the prevention of cancer

Block, F., Gough, A., Prue, G., Solomon-Moore, E., Kesten, J. & Smith, L., 24 Feb 2017, In : International Journal of Play. 6, 1, p. 78-84 7 p.

Research output: Contribution to journalArticle

Exercise
Neoplasms
Sports
Research
Life Style

Time resolved amplified FRET identifies protein kinase B activation state as a marker for poor prognosis in clear cell renal cell carcinoma

Miles, J., Applebee, C., Leboucher, P., Lopez-Fernandez, S., Lee, D-J., Guarch, R., Ward, S., Parker, P., Lopez, J. & Larijani, B., 1 Dec 2017, In : BBA Clinical. 8, p. 97-102 14 p.

Research output: Contribution to journalArticle

Open Access
Proto-Oncogene Proteins c-akt
Renal Cell Carcinoma
Neoplasms
Immunohistochemistry
Activation Analysis

Tobacco control in England: using microsimulation modelling to quantify the potential impact of a tobacco-free generation or a total ban

Kypridemos, C., Reeve, J., Buchan, I., Gilmore, A., Capewell, S. & O'Flaherty, M., 6 Sep 2017.

Research output: Contribution to conferenceAbstract

England
Tobacco
Smoking
Lung Neoplasms
Cardiovascular Diseases
4 Citations (Scopus)

Visualization of Endogenous ERK1/2 in Cells with a Bioorthogonal Covalent Probe

Sipthorp, J., Lebraud, H., Gilley, R., Kidger, A. M., Okkenhaug, H., Saba-El-Leil, M., Meloche, S., Caunt, C. J., Cook, S. J. & Heightman, T. D., 21 Jun 2017, In : Bioconjugate Chemistry. 28, 6, p. 1677-1683 7 p.

Research output: Contribution to journalArticle

Visualization
Proteins
Oncology
Cycloaddition
MAP Kinase Signaling System
2016
4 Citations (Scopus)
229 Downloads (Pure)

Applications of “Hot” and “Cold” Bis(thiosemicarbazonato) Metal Complexes in Multimodal Imaging

Cortezon-Tamarit, F., Sarpaki, S., Calatayud, D. G., Mirabello, V. & Pascu, S. I., 14 Jun 2016, In : Chemical Record. 16, 3, p. 1380-1397 18 p.

Research output: Contribution to journalArticle

Open Access
File
Multimodal Imaging
Coordination Complexes
Metal complexes
Molecular Imaging
Imaging techniques
30 Downloads (Pure)

ART1 induces aberrant methylation of uPA promoter: a preliminary study

Yang, X., Li, M., Wang, Y-L., Threadgill, M., Han, J-Y., Han, X., Chen, L., Chen, H., Hu, W-P. & Lin, X., 15 May 2016, In : International Journal of Clinical and Experimental Pathology. 9, 4, p. 4269-4282

Research output: Contribution to journalArticle

Open Access
File
ADP Ribose Transferases
Methylation
Methyltransferases
DNA
DNA Methylation
12 Citations (Scopus)
68 Downloads (Pure)

A Small Molecule Inhibitor of PDK1/PLCγ1 Interaction Blocks Breast and Melanoma Cancer Cell Invasion

Raimondi, C., Calleja, V., Ferro, R., Fantin, A., Riley, A. M., Potter, B. V. L., Brennan, C. H., Maffucci, T., Larijani, B. & Falasca, M., 20 May 2016, In : Scientific Reports. 6, 26142.

Research output: Contribution to journalArticle

Open Access
File
Phospholipases
Phosphatidylinositols
Protein Kinases
Melanoma
Breast Neoplasms
8 Citations (Scopus)
63 Downloads (Pure)

A study on the AMACR catalysed elimination reaction and its application to inhibitor testing

Jevglevskis, M., Lee, G. L., Sun, J., Zhou, S., Sun, X., Kociok-Kohn, G., James, T. D., Woodman, T. J. & Lloyd, M. D., Jan 2016, In : Organic and Biomolecular Chemistry. 14, 2, p. 612-622

Research output: Contribution to journalArticle

Open Access
File
inhibitors
elimination
Acyl Coenzyme A
Coenzyme A
Assays