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Showing results for cancer as a concept
44 Citations (Scopus)

{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo

Abramkin, S. A., Jungwirth, U., Valiahdi, S. M., Dworak, C., Habala, L., Meelich, K., Berger, W., Jakupec, M. A., Hartinger, C. G., Nazarov, A. A., Galanski, M. & Keppler, B. K., 28 Oct 2010, In : Journal of Medicinal Chemistry. 53, 20, p. 7356-64 9 p.

Research output: Contribution to journalArticle

oxaliplatin
Leukemia L1210
Maximum Tolerated Dose
Cisplatin
Neoplasms
31 Citations (Scopus)

2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents

Leese, M. P., Newman, S. P., Purohit, A., Reed, M. J. & Potter, B. V. L., 2004, In : Bioorganic & Medicinal Chemistry Letters. 14, 12, p. 3135-3138 4 p.

Research output: Contribution to journalArticle

Steryl-Sulfatase
Estrone
Tumors
Estradiol
Estrogens
29 Citations (Scopus)

2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique

Foster, P. A., Ho, Y. T., Newman, S. P., Kasprzyk, P. G., Leese, M. P., Potter, B. V. L., Reed, M. J. & Purohit, A., 2008, In : Breast Cancer Research and Treatment. 111, 2, p. 251-260

Research output: Contribution to journalArticle

Cell Cycle Checkpoints
Heterografts
Apoptosis
Breast Neoplasms
Neoplasms
29 Citations (Scopus)

2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer

Tagg, S. L. C., Foster, P. A., Leese, M. P., Potter, B. V. L., Reed, M. J., Purohit, A. & Newman, S. P., 2008, In : British Journal of Cancer. 99, 11, p. 1842-1848

Research output: Contribution to journalArticle

Deoxyglucose
Prostatic Neoplasms
Breast Neoplasms
Tumor Burden
Heterografts
45 Citations (Scopus)

3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity

Bubert, C., Leese, M. P., Mahon, M. F., Ferrandis, E., Regis-Lydi, S., Kasprzyk, P. G., Newman, S. P., Ho, Y. T., Purohit, A., Reed, M. J. & Potter, B. V. L., 2007, In : Journal of Medicinal Chemistry. 50, 18, p. 4431-4443

Research output: Contribution to journalArticle

Trientine
Steryl-Sulfatase
Carbamates
Estradiol
Neoplasms
36 Citations (Scopus)

5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer

Uribe-lewis, S., Stark, R., Carroll, T., Dunning, M. J., Bachman, M., Ito, Y., Stojic, L., Halim, S., Vowler, S. L., Lynch, A. G., Delatte, B., De Bony, E. J., Colin, L., Defrance, M., Krueger, F., Silva, A., Ten Hoopen, R., Ibrahim, A. E., Fuks, F. & Murrell, A., 1 Apr 2015, In : Genome Biology. 16, 1, p. 1-15 15 p., 69.

Research output: Contribution to journalArticle

Open Access
colon
methylation
cancer
Colon
colorectal neoplasms
7 Citations (Scopus)

A 3D in vitro model of the human breast duct: a method to unravel myoepithelial-luminal interactions in the progression of breast cancer

Carter, E., Gopsill, J., Gomm, J., Jones, L. & Grose, R., 21 Apr 2017, In : Breast Cancer Research. 19, p. 1-10 10 p., 50.

Research output: Contribution to journalArticle

Open Access
Breast
Breast Neoplasms
Tissue Banks
Carcinoma, Intraductal, Noninfiltrating
Mammaplasty
7 Citations (Scopus)
95 Downloads (Pure)
Open Access
File
Habits
Randomized Controlled Trials
Life Style
Exercise
Feeding Behavior
8 Citations (Scopus)

A comparison of two orally bioavailable anti-cancer agents, IRC-110160 and STX140

Foster, P. A., Stengel, C., Ali, T., Leese, M. P., Potter, B. V. L., Reed, M. J., Purohit, A. & Newman, S. P., 2008, In : Anticancer Research. 28, 3A, p. 1483-1491

Research output: Contribution to journalArticle

Neoplasms
Carbonic Anhydrase II
P-Glycoprotein
Hormones
2-methoxyoestra-1,3,5(10),16-tetraene-3-carboxamide
8 Citations (Scopus)
104 Downloads (Pure)

A contrasting function for miR-137 in embryonic mammogenesis and adult breast carcinogenesis

Lee, J. M., Cho, K. W., Kim, E. J., Tang, Q., Kim, K. S., Tickle, C. & Jung, H. S., Sep 2015, In : Oncotarget. 6, 26, p. 22048-22059 12 p.

Research output: Contribution to journalArticle

Open Access
File
Human Mammary Glands
Carcinogenesis
Breast
Breast Neoplasms
MicroRNAs
45 Downloads (Pure)

A convenient colorimetric assay for α-methylacyl-CoA racemase (AMACR; P504S) and testing of inhibitors

Jevglevskis, M., Lee, G. L., Nathubhai, A., James, T., Threadgill, M., Woodman, T. & Lloyd, M., 21 Apr 2017, (Unpublished).

Research output: Contribution to conferenceAbstract

File
Coenzyme A
Inhibitory Concentration 50
Acyl Coenzyme A
Prostatic Neoplasms
S 10

Adipose Tissue Dysfunction

Trim, W., Thompson, D. & Turner, J. E., 2018, Encyclopedia of Behavioral Medicine. New York, U. S. A.: Springer, p. 1-5

Research output: Chapter in Book/Report/Conference proceedingEntry for encyclopedia/dictionary

Adipocytes
Adipose Tissue
Intra-Abdominal Fat
Cellular Structures
Type 2 Diabetes Mellitus
39 Citations (Scopus)
Autoantibodies
Myositis
Interstitial Lung Diseases
Calcinosis
Muscles
34 Citations (Scopus)

Adult cancers near high-voltage overhead power lines

Elliott, P., Shaddick, G., Douglass, M., De Hoogh, K., Briggs, D. J. & Toledano, M. B., Mar 2013, In : Epidemiology. 24, 2, p. 184-190 7 p.

Research output: Contribution to journalArticle

Magnetic Fields
Neoplasms
Breast Neoplasms
Melanoma
Leukemia
8 Citations (Scopus)
22 Downloads (Pure)

Advancing shared decision making for symptom monitoring in people living beyond cancer

Heathcote, L. C., Goldberg, D. S., Eccleston, C., Spunt, S. L., Simons, L. E., Sharpe, L. & Earp, B. D., 1 Oct 2018, In : The Lancet Oncology. 19, 10, p. e556-e563

Research output: Contribution to journalArticle

Open Access
File
Decision Making
Neoplasms
Fear
Recurrence
Quality of Life
3 Citations (Scopus)

A General Method for Motion Compensation in X-ray Computed Tomography

Biguri, A., Dosanjh, M., Hancock, S. & Soleimani, M., 21 Aug 2017, In : Physics in Medicine and Biology. 62, 16, p. 6532–6549 18 p.

Research output: Contribution to journalArticle

Open Access
X Ray Computed Tomography
Artifacts
Tomography
Image-Guided Radiotherapy
Medical Errors
9 Citations (Scopus)

A GWAS on Helicobacter pylori strains points to genetic variants associated with gastric cancer risk

Berthenet, E., Yahara, K., Thorell, K., Pascoe, B., Meric, G., Mikhail, J. M., Engstrand, L., Enroth, H., Burette, A., Megraud, F., Varon, C., Atherton, J. C., Smith, S., Wilkinson, T. S., Hitchings, M. D., Falush, D. & Sheppard, S. K., 2 Aug 2018, In : BMC Biology. 16, p. 1-11 11 p., 84.

Research output: Contribution to journalArticle

Open Access
stomach neoplasms
Helicobacter pylori
Genome-Wide Association Study
Stomach Neoplasms
cancer
3 Citations (Scopus)

A microwave surface applicator for tissue coagulation: Technical characteristics and performances

Lepers, B., Clegg, P., Cronin, N. & Wieland, I., 2012, In : Journal of Medical Devices: Transactions of the ASME. 6, 1, 014502.

Research output: Contribution to journalArticle

Applicators
Microwaves
Coagulation
Tissue
Liver
6 Citations (Scopus)

A motion-compensated cone-beam CT using electrical impedance tomography imaging

Pengpan, T., Smith, N. D., Qiu, W., Yao, A., Mitchell, C. N. & Soleimani, M., Jan 2011, In : Physiological Measurement. 32, 1, p. 19-34

Research output: Contribution to journalArticle

Acoustic impedance
Cone-Beam Computed Tomography
Electric Impedance
Tomography
Cones
63 Citations (Scopus)

An ankyrin-repeat ubiquitin-binding domain determines TRABID's specificity for atypical ubiquitin chains

Licchesi, J. D. F., Mieszczanek, J., Mevissen, T. E. T., Rutherford, T. J., Akutsu, M., Virdee, S., El Oualid, F., Chin, J. W., Ovaa, H., Bienz, M. & Komander, D., 2012, In : Nature Structural and Molecular Biology. 19, 1, p. 62-71 10 p.

Research output: Contribution to journalArticle

Ankyrin Repeat
Ubiquitin
Catalytic Domain
Ankyrins
Biological Phenomena
28 Citations (Scopus)
95 Downloads (Pure)

Anaplastic Lymphoma Kinase is required for neurogenesis in the developing central nervous system of zebrafish

Yao, S., Cheng, M., Zhang, Q., Wasik, M., Kelsh, R. & Winkler, C., 10 May 2013, In : PLoS ONE. 8, 5, e63757.

Research output: Contribution to journalArticle

Open Access
File
neurogenesis
Neurogenesis
Neurology
Zebrafish
lymphoma
30 Citations (Scopus)

A new therapeutic strategy against hormone-dependent breast cancer: the preclinical development of a dual aromatase and sulfatase inhibitor

Foster, P. A., Chander, S. K., Newman, S. P., Woo, L. W. L., Sutcliffe, O. B., Bubert, C., Zhou, D. J., Chen, S. A., Potter, B. V. L., Reed, M. J. & Purohit, A., 15 Oct 2008, In : Clinical Cancer Research. 14, 20, p. 6469-6477

Research output: Contribution to journalArticle

Steryl-Sulfatase
Sulfatases
Aromatase Inhibitors
Aromatase
Hormones
43 Citations (Scopus)

A novel inhibitor of the PI3K/Akt pathway based on the structure of inositol 1,3,4,5,6-pentakisphosphate

Falasca, M., Chiozzotto, D., Godage, H. Y., Mazzoletti, M., Riley, A. M., Previdi, S., Potter, B. V. L., Broggini, M. & Maffucci, T., 5 Jan 2010, In : British Journal of Cancer. 102, 1, p. 104-114

Research output: Contribution to journalArticle

1-Phosphatidylinositol 4-Kinase
Neoplasms
Sirolimus
Phosphatidylinositols
Protein Kinases
18 Citations (Scopus)

A novel mechanism for CTCF in the epigenetic regulation of Bax in breast cancer cells

Méndez-Catalá, C. F., Gretton, S., Vostrov, A., Pugacheva, E., Farrar, D., Ito, Y., Docquier, F., Kita, G-X., Murrell, A., Lobanenkov, V. & Klenova, E., Aug 2013, In : Neoplasia : An International Journal for Oncology Research. 15, 8, p. 898-912 15 p.

Research output: Contribution to journalArticle

Epigenomics
Breast Neoplasms
Binding Sites
bcl-2-Associated X Protein
Breast
7 Citations (Scopus)

A novel silencer element in the bovine papillomavirus type 4 promoter represses the transcriptional response to papillomavirus E2 protein

Vance, K. W., Campo, M. S. & Morgan, I. M., Mar 2001, In : Journal of Virology. 75, 6, p. 2829-38 10 p.

Research output: Contribution to journalArticle

Bovine papillomavirus 4
Bovine papillomavirus
Transcriptional Silencer Elements
Papillomaviridae
Fibroblasts