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Centre for Regenerative Medicine

University of Bath

Organisational unit: Research Centre

Centre for Therapeutic Innovation

University of Bath

Organisational unit: Research Centre

Faculty of Science

University of Bath

Organisational unit: Faculty

University of Bath

Organisational unit: University

Research Output

{(1R,2R,4R)-4-methyl-1,2-cyclohexanediamine}oxalatoplatinum(II): a novel enantiomerically pure oxaliplatin derivative showing improved anticancer activity in vivo

Abramkin, S. A., Jungwirth, U., Valiahdi, S. M., Dworak, C., Habala, L., Meelich, K., Berger, W., Jakupec, M. A., Hartinger, C. G., Nazarov, A. A., Galanski, M. & Keppler, B. K., 28 Oct 2010, In : Journal of Medicinal Chemistry. 53, 20, p. 7356-64 9 p.

Research output: Contribution to journalArticle

44 Citations (Scopus)

2-Alkylsulfanyl estrogen derivatives: synthesis of a novel class of multi-targeted anti-tumour agents

Leese, M. P., Newman, S. P., Purohit, A., Reed, M. J. & Potter, B. V. L., 2004, In : Bioorganic & Medicinal Chemistry Letters. 14, 12, p. 3135-3138 4 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)

2-MeOE2bisMATE and 2-EtE2bisMATE induce cell cycle arrest and apoptosis in breast cancer xenografts as shown by a novel ex vivo technique

Foster, P. A., Ho, Y. T., Newman, S. P., Kasprzyk, P. G., Leese, M. P., Potter, B. V. L., Reed, M. J. & Purohit, A., 2008, In : Breast Cancer Research and Treatment. 111, 2, p. 251-260

Research output: Contribution to journalArticle

29 Citations (Scopus)

2-Methoxyoestradiol-3,17-O,O-bis-sulphamate and 2-deoxy-D-glucose in combination: a potential treatment for breast and prostate cancer

Tagg, S. L. C., Foster, P. A., Leese, M. P., Potter, B. V. L., Reed, M. J., Purohit, A. & Newman, S. P., 2008, In : British Journal of Cancer. 99, 11, p. 1842-1848

Research output: Contribution to journalArticle

31 Citations (Scopus)

3,17-disubstituted 2-alkylestra-1,3,5(10)-trien-3-ol derivatives: synthesis, in vitro and in vivo anticancer activity

Bubert, C., Leese, M. P., Mahon, M. F., Ferrandis, E., Regis-Lydi, S., Kasprzyk, P. G., Newman, S. P., Ho, Y. T., Purohit, A., Reed, M. J. & Potter, B. V. L., 2007, In : Journal of Medicinal Chemistry. 50, 18, p. 4431-4443

Research output: Contribution to journalArticle

45 Citations (Scopus)

5-hydroxymethylcytosine marks promoters in colon that resist DNA hypermethylation in cancer

Uribe-lewis, S., Stark, R., Carroll, T., Dunning, M. J., Bachman, M., Ito, Y., Stojic, L., Halim, S., Vowler, S. L., Lynch, A. G., Delatte, B., De Bony, E. J., Colin, L., Defrance, M., Krueger, F., Silva, A., Ten Hoopen, R., Ibrahim, A. E., Fuks, F. & Murrell, A., 1 Apr 2015, In : Genome Biology. 16, 1, p. 1-15 15 p., 69.

Research output: Contribution to journalArticle

Open Access
38 Citations (Scopus)

Projects

Deciphering the Dandida Albicans Hsp90 Kinase Interactome

Diezmann, S.

Medical Research Council

28/07/1422/02/18

Project: Research council