Zebrafish genetics gets the Scube on Hedgehog secretion

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3 Citations (SciVal)

Abstract

Inspired by a zebrafish mutation, two recent studies by Creanga and colleagues (pp. 1312-1325) and Tukachinsky and colleagues have shed new light on the way in which lipidated Hedgehog proteins are secreted and released from expressing cells, suggesting a model for the sequential action of the Disp and Scube2 proteins in this process.

Original languageEnglish
Pages (from-to)2468-2470
Number of pages3
JournalGenes & Development
Volume26
Issue number22
DOIs
Publication statusPublished - 15 Nov 2012

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