Why some screening hits are a PAIN

Research output: Contribution to specialist publicationArticle

Abstract

A major challenge during high-throughput and fragment screening is the potential for identifying ‘frequent hitters’ – compounds that affect unrelated targets. Matthew Lloyd from the University of Bath explains why these hits can arise during drug discovery and how machine learning could be the answer to identifying these compounds.
Original languageEnglish
Pages42-44
Number of pages3
Volume8
No.2
Specialist publicationDrug Target Review
Publication statusPublished - 7 Jun 2021

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