Who should we ask about mental health symptoms in adolescents with CFS/ME? Parent-child agreement on the Revised Children’s Anxiety and Depression Scale

Teona Serafimova, Maria Loades, Daisy Gaunt, Esther Crawley

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Abstract

Background:

One in three adolescents with chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME) have mental health problems. Multi-informant perspectives are key to psychological assessment. Understanding parent-child agreement is crucial to accurate diagnosis, particularly where severe fatigue limits self-report.
Methods:

Agreement on the revised children’s anxiety and depression scale (RCADs) was assessed between parents and children with CFS/ME (n = 93) using Bland-Altman plots, cross tabulations and regression analyses.
Results:

Diagnostic thresholds were met more frequently based on child-report. Parent- and child-report had similar sensitivity and specificity on RCADS compared to gold-standard diagnostic interviews. Regression analysis found similar accuracy between both reports. For anxiety diagnoses, odds ratio (OR) for child-report was 1.10 (CI = 1.06–1.14), and 1.10 (CI = 1.05–1.14) for parent-report. For depression, OR for child report was 1.26 (CI = 1.11–1.43), while for parent-report is was 1.25 (CI = 1.10–1.41). For total score, OR for child-report was 1.10 (CI = 1.05–1.13) while OR for parent-report was 1.09 (CI = 1.05–1.13).
Conclusions:

Reasonable agreement was observed between parent- and child-report of mental health symptoms in paediatric CFS/ME. While parent-report can facilitate psychological evaluation in CFS/ME, this is not a substitute for a child’s own report.
Original languageEnglish
Pages (from-to)367-380
Number of pages14
JournalClinical Child Psychology and Psychiatry
Volume26
Issue number2
Early online date15 Feb 2021
DOIs
Publication statusPublished - 30 Apr 2021

Funding

The author(s) disclosed receipt of the following financial support for the research, authorship, and/or publication of this article: This study received no specific funding. Professor Crawley was funded, during data collection, by the National Institute for Health Research (Senior Research Fellowship, SRF-2013-06-013). Dr Loades is funded by a NIHR Doctoral Research Fellowship (DRF-2016-09-021). This report is independent research. The views expressed in this publication are those of the authors(s) and not necessarily those of the NHS, NIHR or the Department of Health and Social Care.

FundersFunder number
National Institute for Health ResearchDRF-2016-09-021, SRF-2013-06-013

Keywords

  • Chronic fatigue syndrome
  • anxiety
  • depression
  • myalgic encephalomyelitis
  • paediatric chronic fatigue syndrome
  • parent child agreement

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Psychology
  • Psychiatry and Mental health

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