UVA-Triggered Drug Release and Photo-Protection of Skin

Vega Widya Karisma; Wei Wu; Mingxing  Lei; Huawen  Liu; Muhammad Farrukh  Nisar; Matthew Lloyd; Charareh Pourzand; Julia Li Zhong

doi:10.3389/fcell.2021.598717

UVA-Triggered Drug Release and Photo-Protection of Skin

Vega Widya Karisma, Wei Wu, Mingxing Lei, Huawen Liu, Muhammad Farrukh Nisar, Matthew Lloyd, Charareh Pourzand, Julia Li Zhong

Research output: Contribution to journal › Article › peer-review

12 Citations (SciVal)

Abstract

Light has attracted special attention as a stimulus for triggered drug delivery systems (DDS) due to its intrinsic features of being spatially and temporally tunable. Ultraviolet A (UVA) radiation has recently been used as a source of external light stimuli to control the release of drugs using a “switch on- switch off” procedure. This review discusses the promising potential of UVA radiation as the light source of choice for photo-controlled drug release from a range of photo-responsive and photolabile nanostructures via photo-isomerization, photo-cleavage, photo-crosslinking and photo-induced rearrangement. In addition to its clinical use, we will also provide here an overview of the recent UVA-responsive drug release approaches that are developed for phototherapy and skin photoprotection.

Original language	English
Article number	598717
Journal	Frontiers in Cell and Developmental Biology
Volume	9
DOIs	https://doi.org/10.3389/fcell.2021.598717
Publication status	Published - 11 Feb 2021

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https://www.frontiersin.org/articles/10.3389/fcell.2021.598717/abstractLicence: CC BY

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title = "UVA-Triggered Drug Release and Photo-Protection of Skin",

abstract = "Light has attracted special attention as a stimulus for triggered drug delivery systems (DDS) due to its intrinsic features of being spatially and temporally tunable. Ultraviolet A (UVA) radiation has recently been used as a source of external light stimuli to control the release of drugs using a “switch on- switch off” procedure. This review discusses the promising potential of UVA radiation as the light source of choice for photo-controlled drug release from a range of photo-responsive and photolabile nanostructures via photo-isomerization, photo-cleavage, photo-crosslinking and photo-induced rearrangement. In addition to its clinical use, we will also provide here an overview of the recent UVA-responsive drug release approaches that are developed for phototherapy and skin photoprotection.",

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AU - Karisma, Vega Widya

AU - Wu, Wei

AU - Lei, Mingxing

AU - Liu, Huawen

AU - Nisar, Muhammad Farrukh

AU - Lloyd, Matthew

AU - Pourzand, Charareh

AU - Li Zhong, Julia

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AB - Light has attracted special attention as a stimulus for triggered drug delivery systems (DDS) due to its intrinsic features of being spatially and temporally tunable. Ultraviolet A (UVA) radiation has recently been used as a source of external light stimuli to control the release of drugs using a “switch on- switch off” procedure. This review discusses the promising potential of UVA radiation as the light source of choice for photo-controlled drug release from a range of photo-responsive and photolabile nanostructures via photo-isomerization, photo-cleavage, photo-crosslinking and photo-induced rearrangement. In addition to its clinical use, we will also provide here an overview of the recent UVA-responsive drug release approaches that are developed for phototherapy and skin photoprotection.

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UVA-Triggered Drug Release and Photo-Protection of Skin

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UVA-Triggered Drug Release and Photo-Protection of Skin

Abstract

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Mitochondria-Targeted Iron Chelators for the Therapy of Parkinson's Disease

Light-Activated Caged-Iron Chelator for Skin Photoprotection based on the Natural Product Pulcherrimic Acid

Cite this