Projects per year
Abstract
Background: Heterotrophic single-cell oils (SCOs) are one potential replacement to lipid-derived biofuels sourced from first-generation crops such as palm oil. However, despite a large experimental research effort in this area, there are only a handful of techno-economic modelling publications. As such, there is little understanding of whether SCOs are, or could ever be, a potential competitive replacement. To help address this question, we designed a detailed model that coupled a hypothetical heterotroph (using the very best possible biological lipid production) with the largest and most efficient chemical plant design possible. Results: Our base case gave a lipid selling price of $1.81/kg for ~ 8,000 tonnes/year production, that could be reduced to $1.20/kg on increasing production to ~ 48,000 tonnes of lipid a year. A range of scenarios to further reduce this cost were then assessed, including using a thermotolerant strain (reducing the cost from $1.20 to $1.15/kg), zero-cost electricity ($ 1.12/kg), using non-sterile conditions ($1.19/kg), wet extraction of lipids ($1.16/kg), continuous production of extracellular lipid ($0.99/kg) and selling the whole yeast cell, including recovering value for the protein and carbohydrate ($0.81/kg). If co-products were produced alongside the lipid then the price could be effectively reduced to $0, depending on the amount of carbon funnelled away from lipid production, as long as the co-product could be sold in excess of $1/kg. Conclusions: The model presented here represents an ideal case that which while not achievable in reality, importantly would not be able to be improved on, irrespective of the scientific advances in this area. From the scenarios explored, it is possible to produce lower cost SCOs, but research must start to be applied in three key areas, firstly designing products where the whole cell is used. Secondly, further work on the product systems that produce lipids extracellularly in a continuous processing methodology or finally that create an effective biorefinery designed to produce a low molecular weight, bulk chemical, alongside the lipid. All other research areas will only ever give incremental gains rather than leading towards an economically competitive, sustainable, microbial oil.
Original language | English |
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Article number | 57 |
Journal | Biotechnology for Biofuels |
Volume | 14 |
Issue number | 1 |
Early online date | 4 Mar 2021 |
DOIs | |
Publication status | Published - 31 Dec 2021 |
Acknowledgements
In addition, the authors would like to extend their thanks for the invaluable advice from Dr Phil Pienkos (NREL), Dr. Peter Turner (Breakthrough Energy Ventures) and Prof. Ioannis Kookos (University of Patras).Keywords
- Lipid
- Single cell oil
- TEA
- Techno-economic analysis
ASJC Scopus subject areas
- Biotechnology
- Applied Microbiology and Biotechnology
- Renewable Energy, Sustainability and the Environment
- General Energy
- Management, Monitoring, Policy and Law
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Dive into the research topics of 'Using techno-economic modelling to determine the minimum cost possible for a microbial palm oil substitute'. Together they form a unique fingerprint.Projects
- 4 Finished
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Energy Systems and Resource Impact Management Framework - Dynamic Energy Planning: Global and National Resilience
McManus, M. (PI)
Engineering and Physical Sciences Research Council
1/03/17 → 28/02/18
Project: Research council
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Integrated Energy Efficient Microwave and Unique Fermentation Processes for Pilot Scale Production of High Value Chemical from Lignocellulosic Waste
Chuck, C. (PI), Henk, D. (CoI), Leak, D. (CoI), McManus, M. (CoI) & Scott, R. (CoI)
Engineering and Physical Sciences Research Council
1/03/16 → 31/01/21
Project: Research council
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Exploring the Integration of CCA into Early Stage Bioenergy Research
McManus, M. (PI)
Biotechnology and Biological Sciences Research Council
1/04/13 → 31/03/15
Project: Research council