Urinary bladder innervation within the sacral roots of a sheep

B. Metcalfe, N. Granger, J. Prager, L. Jabban, J. Taylor, S. Sadrafshari, N. Donaldson

Research output: Chapter or section in a book/report/conference proceedingChapter in a published conference proceeding

Abstract

Managing the urinary bladder after spinal cord injury is of primary importance because neurogenic dysfunction leads to life-threatening complications. Sacral Anterior Root Stimulators that control the bladder have been available for many years, however, these devices cannot sense the fullness of the bladder or detect the onset of reflex voiding. In order to address this fundamental limitation, this paper explores the possibility of recording the neural signals that encode bladder fullness from the sacral roots in sheep using extra-neural books. Stimulation of and recording from six roots (S1, S2 and S3 bilaterally) shows that efferent and afferent pathways seem to be co-located within roots, but also that simultaneous recording from multiple roots may be useful to enhance overall signal quality.

Original languageEnglish
Title of host publication2021 10th International IEEE/EMBS Conference on Neural Engineering, NER 2021
PublisherIEEE
Pages605-608
Number of pages4
ISBN (Electronic)9781728143378
ISBN (Print)978-1-7281-4338-5
DOIs
Publication statusPublished - 2 Jun 2021
Event10th International IEEE/EMBS Conference on Neural Engineering, NER 2021 - Virtual, Online, Italy
Duration: 4 May 20216 May 2021

Publication series

NameInternational IEEE/EMBS Conference on Neural Engineering, NER
Volume2021-May
ISSN (Print)1948-3546
ISSN (Electronic)1948-3554

Conference

Conference10th International IEEE/EMBS Conference on Neural Engineering, NER 2021
Country/TerritoryItaly
CityVirtual, Online
Period4/05/216/05/21

ASJC Scopus subject areas

  • Artificial Intelligence
  • Mechanical Engineering

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