Untimely ends and new beginnings in mouse cloning

Anthony C F Perry; T Wakayama

doi:10.1038/ng0302-243

Untimely ends and new beginnings in mouse cloning

Anthony C F Perry, T Wakayama

Department of Life Sciences

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38 Citations (SciVal)

Abstract

A new study shows that the majority of mice cloned from somatic cells die prematurely. Of the six dead clones analyzed, four exhibited extensive necrosis of the liver, two had tumors and all had pneumonia, suggestive of immune impairment. These latest cloning-associated phenotypes will facilitate a better understanding of the mechanisms underlying nuclear-transfer cloning in mammals.

Original language	English
Pages (from-to)	243-244
Number of pages	2
Journal	Nature Genetics
Volume	30
Issue number	3
DOIs	https://doi.org/10.1038/ng0302-243
Publication status	Published - 2002

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abstract = "A new study shows that the majority of mice cloned from somatic cells die prematurely. Of the six dead clones analyzed, four exhibited extensive necrosis of the liver, two had tumors and all had pneumonia, suggestive of immune impairment. These latest cloning-associated phenotypes will facilitate a better understanding of the mechanisms underlying nuclear-transfer cloning in mammals.",

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Untimely ends and new beginnings in mouse cloning

Abstract

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