Untimely ends and new beginnings in mouse cloning

Anthony C F Perry, T Wakayama

Research output: Contribution to journalArticle

33 Citations (Scopus)

Abstract

A new study shows that the majority of mice cloned from somatic cells die prematurely. Of the six dead clones analyzed, four exhibited extensive necrosis of the liver, two had tumors and all had pneumonia, suggestive of immune impairment. These latest cloning-associated phenotypes will facilitate a better understanding of the mechanisms underlying nuclear-transfer cloning in mammals.
LanguageEnglish
Pages243-244
Number of pages2
JournalNature Genetics
Volume30
Issue number3
DOIs
StatusPublished - 2002

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Organism Cloning
Mammals
Pneumonia
Necrosis
Clone Cells
Phenotype
Liver
Neoplasms

Cite this

Untimely ends and new beginnings in mouse cloning. / Perry, Anthony C F; Wakayama, T.

In: Nature Genetics, Vol. 30, No. 3, 2002, p. 243-244.

Research output: Contribution to journalArticle

Perry, Anthony C F ; Wakayama, T. / Untimely ends and new beginnings in mouse cloning. In: Nature Genetics. 2002 ; Vol. 30, No. 3. pp. 243-244.
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