TY - JOUR
T1 - Ultrasound promoted Wurtz coupling of alkyl bromides and dibromides
AU - Vandenburg, Daniel
AU - Price, Gareth J
PY - 2012
Y1 - 2012
N2 - Sonochemically enhanced Wurtz coupling using lithium metal has been investigated for a number of isomeric alkyl bromides under a variety conditions. The products result from direct coupling of short lived radicals formed at the metal surface rather than the secondary radicals which can be formed during coupling of aromatic halides and thus give rise to a single major product. Coupling has been extended to dibrominated aryl and alkyl compounds as well as showing that aryl-alkyl coupling is possible. Dibrominated alkyls were found to give low molecular weight oligomers although no reaction occurred for 1,2-isomers. The growth of oligomers in THF may be solubility limited. A simple model is proposed to explain these findings.
AB - Sonochemically enhanced Wurtz coupling using lithium metal has been investigated for a number of isomeric alkyl bromides under a variety conditions. The products result from direct coupling of short lived radicals formed at the metal surface rather than the secondary radicals which can be formed during coupling of aromatic halides and thus give rise to a single major product. Coupling has been extended to dibrominated aryl and alkyl compounds as well as showing that aryl-alkyl coupling is possible. Dibrominated alkyls were found to give low molecular weight oligomers although no reaction occurred for 1,2-isomers. The growth of oligomers in THF may be solubility limited. A simple model is proposed to explain these findings.
UR - http://www.scopus.com/inward/record.url?scp=80051469137&partnerID=8YFLogxK
UR - http://dx.doi.org/10.1016/j.ultsonch.2011.06.002
U2 - 10.1016/j.ultsonch.2011.06.002
DO - 10.1016/j.ultsonch.2011.06.002
M3 - Article
VL - 19
SP - 5
EP - 8
JO - Ultrasonics Sonochemistry
JF - Ultrasonics Sonochemistry
SN - 1350-4177
IS - 1
ER -