This chapter outlines bioreactor design for soft tissue, using a bioprocessing approach. Bioreactor configurations are reviewed, and as bioreactor performance is intimately related to the scaffold, materials and scaffold architecture are described. Mass transfer considerations, bioreactor data collection and how to take a bioprocessing approach to bioreactor design are described, with an example of liver tissue engineering.
|Title of host publication||Standardisation in Cell and Tissue Engineering: Methods and Protocols|
|Subtitle of host publication||Methods and Protocols|
|Publisher||Woodhead Publishing Ltd.|
|Number of pages||20|
|Publication status||Published - 2013|
Ellis, M. J. (2013). Two- and three-dimensional tissue culture bioprocessing methods for soft tissue engineering. In Standardisation in Cell and Tissue Engineering: Methods and Protocols: Methods and Protocols (pp. 34-53). Woodhead Publishing Ltd.. https://doi.org/10.1533/9780857098726.1.34