Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

A G Watts; I Damager; M L Amaya; A Buschiazzo; P M Alzari; A C Frasch; S G Withers

doi:10.1021/ja0344967

Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

A G Watts, I Damager, M L Amaya, A Buschiazzo, P M Alzari, A C Frasch, S G Withers

Department of Pharmacy & Pharmacology

Research output: Contribution to journal › Article › peer-review

178 Citations (SciVal)

Original language	English
Pages (from-to)	7532-7533
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	125
Issue number	25
DOIs	https://doi.org/10.1021/ja0344967
Publication status	Published - 2003

Access to Document

10.1021/ja0344967

Cite this

Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile. / Watts, A G; Damager, I; Amaya, M L; Buschiazzo, A; Alzari, P M; Frasch, A C; Withers, S G.

In: Journal of the American Chemical Society, Vol. 125, No. 25, 2003, p. 7532-7533.

Research output: Contribution to journal › Article › peer-review

@article{21b2f815e09946468d86c05042d1a8bb,

title = "Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile",

author = "Watts, {A G} and I Damager and Amaya, {M L} and A Buschiazzo and Alzari, {P M} and Frasch, {A C} and Withers, {S G}",

year = "2003",

doi = "10.1021/ja0344967",

language = "English",

volume = "125",

pages = "7532--7533",

journal = "Journal of the American Chemical Society",

issn = "0002-7863",

publisher = "American Chemical Society",

number = "25",

}

TY - JOUR

T1 - Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

AU - Watts, A G

AU - Damager, I

AU - Amaya, M L

AU - Buschiazzo, A

AU - Alzari, P M

AU - Frasch, A C

AU - Withers, S G

PY - 2003

Y1 - 2003

UR - http://dx.doi.org/10.1021/ja0344967

U2 - 10.1021/ja0344967

DO - 10.1021/ja0344967

M3 - Article

VL - 125

SP - 7532

EP - 7533

JO - Journal of the American Chemical Society

JF - Journal of the American Chemical Society

SN - 0002-7863

IS - 25

ER -

Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

Access to Document

Other files and links

Cite this