Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

A G Watts; I Damager; M L Amaya; A Buschiazzo; P M Alzari; A C Frasch; S G Withers

doi:10.1021/ja0344967

Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile

A G Watts, I Damager, M L Amaya, A Buschiazzo, P M Alzari, A C Frasch, S G Withers

Department of Pharmacy & Pharmacology

Research output: Contribution to journal › Article › peer-review

175 Citations (Scopus)

Original language	English
Pages (from-to)	7532-7533
Number of pages	2
Journal	Journal of the American Chemical Society
Volume	125
Issue number	25
DOIs	https://doi.org/10.1021/ja0344967
Publication status	Published - 2003

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10.1021/ja0344967

http://dx.doi.org/10.1021/ja0344967

Cite this

Trypanosoma cruzi trans-sialidase operates through a covalent sialyl-enzyme intermediate: tyrosine is the catalytic nucleophile. / Watts, A G; Damager, I; Amaya, M L; Buschiazzo, A; Alzari, P M; Frasch, A C; Withers, S G.

In: Journal of the American Chemical Society, Vol. 125, No. 25, 2003, p. 7532-7533.

Research output: Contribution to journal › Article › peer-review

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AU - Frasch, A C

AU - Withers, S G

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