Transposition: A CRISPR Way to Get Around

Tatiana Dimitriu; Ben Ashby; Edze Westra

doi:10.1016/j.cub.2019.08.010

Transposition: A CRISPR Way to Get Around

Tatiana Dimitriu, Ben Ashby, Edze Westra

Department of Mathematical Sciences

University of Exeter

Research output: Contribution to journal › Article

6 Citations (SciVal)

77 Downloads (Pure)

Abstract

CRISPR-Cas systems provide sequence-specific immunity against selfish genetic elements in prokaryotes. Now, two studies show that transposon-encoded variants can guide sequence-specific transposition. These findings have important practical implications but also raise questions of why and how this strategy would benefit transposons.

Original language	English
Pages (from-to)	R886-R889
Number of pages	4
Journal	Current Biology
Volume	29
Issue number	18
Early online date	23 Sept 2019
DOIs	https://doi.org/10.1016/j.cub.2019.08.010
Publication status	Published - 23 Sept 2019

Keywords

CRISPR
transposable element
Transposons

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10.1016/j.cub.2019.08.010

Dimitriu et al 2019 - Transposition- A CRISPR way to get around.PDFAccepted author manuscript, 468 KBLicence: CC BY-NC-ND

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title = "Transposition: A CRISPR Way to Get Around",

abstract = "CRISPR-Cas systems provide sequence-specific immunity against selfish genetic elements in prokaryotes. Now, two studies show that transposon-encoded variants can guide sequence-specific transposition. These findings have important practical implications but also raise questions of why and how this strategy would benefit transposons.",

keywords = "CRISPR, transposable element, Transposons",

author = "Tatiana Dimitriu and Ben Ashby and Edze Westra",

year = "2019",

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AU - Westra, Edze

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AB - CRISPR-Cas systems provide sequence-specific immunity against selfish genetic elements in prokaryotes. Now, two studies show that transposon-encoded variants can guide sequence-specific transposition. These findings have important practical implications but also raise questions of why and how this strategy would benefit transposons.

KW - CRISPR

KW - transposable element

KW - Transposons

UR - https://www.scopus.com/pages/publications/85072259601

U2 - 10.1016/j.cub.2019.08.010

DO - 10.1016/j.cub.2019.08.010

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SN - 0960-9822

VL - 29

SP - R886-R889

JO - Current Biology

JF - Current Biology

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ER -

Transposition: A CRISPR Way to Get Around

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Keywords

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Fellowship Ben Ashby - Host-parasite Coevolution in Complex Communities

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Transposition: A CRISPR Way to Get Around

Abstract

Keywords

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Fellowship Ben Ashby - Host-parasite Coevolution in Complex Communities

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