TY - JOUR
T1 - Transition-Metal-Mediated Functionalization of White Phosphorus
AU - Hoidn, Christian
AU - Scott, Daniel
AU - Wolf, Robert
N1 - R.W.would like thank a number of dedicated former and present co-workers for their vital contributionsto the group’s research in the field. Their names are in the references. In addition, generous financial support by the European Research Council (CoG772299), the Alexander von Humboldt foundation (fellowship to D.J.S.), and the Stiftung der Deutschen Wirtschaft (sdw, PhD scholarship to C.M.H.) is gratefully acknowledged. Open access funding enabled and organized by Projekt DEAL.
PY - 2021/1/26
Y1 - 2021/1/26
N2 - Recently there has been great interest in the reactivity of transition-metal (TM) centers towards white phosphorus (P4). This has ultimately been motivated by a desire to find TM-mediated alternatives to the current industrial routes used to transform P4 into myriad useful P-containing products, which are typically indirect, wasteful, and highly hazardous. Such a TM-mediated process can be divided into two steps: activation of P4 to generate a polyphosphorus complex TM-Pn, and subsequent functionalization of this complex to release the desired phosphorus-containing product. The former step has by now become well established, allowing the isolation of many different TM-Pn products. In contrast, productive functionalization of these complexes has proven extremely challenging and has been achieved only in a relative handful of cases. In this review we provide a comprehensive summary of successful TM-Pn functionalization reactions, where TM-Pn must be accessible by reaction of a TM precursor with P4. We hope that this will provide a useful resource for continuing efforts that are working towards this highly challenging goal of modern synthetic chemistry.
AB - Recently there has been great interest in the reactivity of transition-metal (TM) centers towards white phosphorus (P4). This has ultimately been motivated by a desire to find TM-mediated alternatives to the current industrial routes used to transform P4 into myriad useful P-containing products, which are typically indirect, wasteful, and highly hazardous. Such a TM-mediated process can be divided into two steps: activation of P4 to generate a polyphosphorus complex TM-Pn, and subsequent functionalization of this complex to release the desired phosphorus-containing product. The former step has by now become well established, allowing the isolation of many different TM-Pn products. In contrast, productive functionalization of these complexes has proven extremely challenging and has been achieved only in a relative handful of cases. In this review we provide a comprehensive summary of successful TM-Pn functionalization reactions, where TM-Pn must be accessible by reaction of a TM precursor with P4. We hope that this will provide a useful resource for continuing efforts that are working towards this highly challenging goal of modern synthetic chemistry.
U2 - 10.1002/chem.202001854
DO - 10.1002/chem.202001854
M3 - Review article
SN - 0947-6539
VL - 27
SP - 1886
EP - 1902
JO - Chemistry - A European Journal
JF - Chemistry - A European Journal
IS - 6
ER -