Transdifferentiation of Cells and Tissues

Jonathan Slack (Inventor), Marko Horb (Inventor), David Tosh (Inventor)

Research output: Patent


Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.
Original languageEnglish
Patent numberWO03078636 (A1)
IPCC07K14/005,C07K14/4702 ,C12N5/0676
Priority date18/03/02
Publication statusPublished - 25 Sept 2003


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