Transdifferentiation of Cells and Tissues

Jonathan Slack; Marko Horb; David Tosh

Transdifferentiation of Cells and Tissues

Jonathan Slack (Inventor), Marko Horb (Inventor), David Tosh (Inventor)

Department of Biology & Biochemistry

Research output: Patent

Abstract

Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.

Original language	English
Patent number	WO03078636 (A1)
IPC	C07K14/035
Publication status	Published - 25 Sep 2003

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title = "Transdifferentiation of Cells and Tissues",

abstract = "Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.",

author = "Jonathan Slack and Marko Horb and David Tosh",

year = "2003",

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language = "English",

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AB - Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.

M3 - Patent

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