Transdifferentiation of Cells and Tissues

Jonathan Slack; Marko Horb; David Tosh

Transdifferentiation of Cells and Tissues

Jonathan Slack (Inventor), Marko Horb (Inventor), David Tosh (Inventor)

Department of Life Sciences

Research output: Patent

Abstract

Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.

Original language	English
Patent number	WO03078636 (A1)
IPC	C07K14/005,C07K14/4702 ,C12N5/0676
Priority date	18/03/02
Publication status	Published - 25 Sept 2003

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title = "Transdifferentiation of Cells and Tissues",

abstract = "Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.",

author = "Jonathan Slack and Marko Horb and David Tosh",

year = "2003",

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T1 - Transdifferentiation of Cells and Tissues

AU - Slack, Jonathan

AU - Horb , Marko

AU - Tosh, David

PY - 2003/9/25

Y1 - 2003/9/25

N2 - Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.

AB - Method for carrying out transdifferentiation of non-pancreatic cells to pancreatic cells involving the provision of a pancreas specific transcription factor and an activating means such as VP16 of Herpes simplex virus to non-pancreatic cells. The methods and materials provided by the invention may be used to treat pancreatic disorders, in particular disorders caused by a loss of properly functioning pancreas such as pancreatic cancer and diabetes.

UR - https://worldwide.espacenet.com/patent/search/family/009933199/publication/WO03078636A1?q=pn%3DEP1485485A1

M3 - Patent

M1 - WO03078636 (A1)

ER -

Transdifferentiation of Cells and Tissues

Abstract

UN SDGs

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