Transdermal drug delivery to neonates

N. Evans; R. H. Guy; J. Hadgraft; G. D. Parr; N. Rutter

doi:10.1016/0378-5173(85)90025-0

Transdermal drug delivery to neonates

N. Evans, R. H. Guy, J. Hadgraft, G. D. Parr, N. Rutter

Research output: Contribution to journal › Article › peer-review

Abstract

A pharmacokinetic model has been formulated to assess the potential of transdermal drug delivery to preterm infants. The permeability of the skin in these infants is high and this route of administration may prove a suitable means of delivering many drugs. Theoretical equations show how the rate of drug delivery influences the plasma levels of the topically applied drugs.

Original language	English
Pages (from-to)	259-265
Number of pages	7
Journal	International Journal of Pharmaceutics
Volume	24
Issue number	2-3
DOIs	https://doi.org/10.1016/0378-5173(85)90025-0
Publication status	Published - May 1985

Bibliographical note

Funding Information:
We would like to thank Vick Internationalf or financial supporta nd MRC grant to supportN .E.

Keywords

neonate
percutaneous absorption
pharmacokinetic model
transdermal delivery

ASJC Scopus subject areas

Pharmaceutical Science

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10.1016/0378-5173(85)90025-0

Cite this

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title = "Transdermal drug delivery to neonates",

abstract = "A pharmacokinetic model has been formulated to assess the potential of transdermal drug delivery to preterm infants. The permeability of the skin in these infants is high and this route of administration may prove a suitable means of delivering many drugs. Theoretical equations show how the rate of drug delivery influences the plasma levels of the topically applied drugs.",

keywords = "neonate, percutaneous absorption, pharmacokinetic model, transdermal delivery",

author = "N. Evans and Guy, {R. H.} and J. Hadgraft and Parr, {G. D.} and N. Rutter",

note = "Funding Information: We would like to thank Vick Internationalf or financial supporta nd MRC grant to supportN .E.",

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AU - Evans, N.

AU - Guy, R. H.

AU - Hadgraft, J.

AU - Parr, G. D.

AU - Rutter, N.

N1 - Funding Information: We would like to thank Vick Internationalf or financial supporta nd MRC grant to supportN .E.

PY - 1985/5

Y1 - 1985/5

N2 - A pharmacokinetic model has been formulated to assess the potential of transdermal drug delivery to preterm infants. The permeability of the skin in these infants is high and this route of administration may prove a suitable means of delivering many drugs. Theoretical equations show how the rate of drug delivery influences the plasma levels of the topically applied drugs.

AB - A pharmacokinetic model has been formulated to assess the potential of transdermal drug delivery to preterm infants. The permeability of the skin in these infants is high and this route of administration may prove a suitable means of delivering many drugs. Theoretical equations show how the rate of drug delivery influences the plasma levels of the topically applied drugs.

KW - neonate

KW - percutaneous absorption

KW - pharmacokinetic model

KW - transdermal delivery

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ER -

Transdermal drug delivery to neonates

Abstract

Bibliographical note

Keywords

ASJC Scopus subject areas

Access to Document

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