592 Citations (SciVal)

Abstract

The skin represents an extraordinary evolutionary feat. Not only does it physically encapsulate the organism and provide a multifunctional interface between us and our surroundings, but it is perpetually engaged in the assembly of a highly efficient homeostatic barrier to the outward loss of water. In so doing, it furnishes a membrane that is equally adept at limiting molecular transport both from and into the body. Overcoming this barrier function then, for the purpose of transdermal drug delivery, has been a necessarily challenging task for the pharmaceutical scientist, and one that boasts significant progress.

Original languageEnglish
Pages (from-to)318-326
Number of pages9
JournalPharmaceutical Science and Technology Today
Volume3
Issue number9
DOIs
Publication statusPublished - 1 Sept 2000

ASJC Scopus subject areas

  • Pharmaceutical Science

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