Abstract
Part one of this two-part review addresses the transport of therapeutics across the intestinal barrier, and focuses on transcellular transport through the intestinal epithelia. The anatomical, biochemical and physiological parameters impacting transcellular uptake of orally administered drugs are described, and methods for overcoming obstacles limiting successful transcellular oral drug delivery are discussed. Part two will cover paracellular transport.
Original language | English |
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Pages (from-to) | 144-151 |
Number of pages | 8 |
Journal | Pharmaceutical Science and Technology Today |
Volume | 2 |
Issue number | 4 |
DOIs | |
Publication status | Published - 1 Apr 1999 |
ASJC Scopus subject areas
- Pharmaceutical Science