Transamidation of primary amides with amines catalyzed by zirconocene dichloride

Benjamin N. Atkinson, A. Rosie Chhatwal, Helen V. Lomax, James W. Walton, Jonathan M. J. Williams

Research output: Contribution to journalArticlepeer-review

72 Citations (Scopus)
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Abstract

Zirconocene dichloride (Cp2ZrCl2) has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80 °C in 5–24 hours. For favourable substrates, the reaction can be performed at temperatures as low as 30 °C.
Original languageEnglish
Pages (from-to)11626-11628
Number of pages3
JournalChemical Communications
Volume48
Issue number95
DOIs
Publication statusPublished - 11 Dec 2012

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