Transamidation of primary amides with amines catalyzed by zirconocene dichloride

Benjamin N. Atkinson, A. Rosie Chhatwal, Helen V. Lomax, James W. Walton, Jonathan M. J. Williams

Research output: Contribution to journalArticle

69 Citations (Scopus)
175 Downloads (Pure)

Abstract

Zirconocene dichloride (Cp2ZrCl2) has been shown to be an effective catalyst for the transamidation of primary amides with amines in cyclohexane at 80 °C in 5–24 hours. For favourable substrates, the reaction can be performed at temperatures as low as 30 °C.
Original languageEnglish
Pages (from-to)11626-11628
Number of pages3
JournalChemical Communications
Volume48
Issue number95
DOIs
Publication statusPublished - 11 Dec 2012

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  • Projects

    Dream Fellowship

    Williams, J.

    Engineering and Physical Sciences Research Council

    1/08/1110/05/13

    Project: Research council

  • Cite this

    Atkinson, B. N., Chhatwal, A. R., Lomax, H. V., Walton, J. W., & Williams, J. M. J. (2012). Transamidation of primary amides with amines catalyzed by zirconocene dichloride. Chemical Communications, 48(95), 11626-11628. https://doi.org/10.1039/c2cc37427g