Trans-saccadic memory after right parietal brain damage

Antonia F. Ten Brink, Jasper H. Fabius, Nick A. Weaver, Tanja C.W. Nijboer, Stefan Van der Stigchel

Research output: Contribution to journalArticle

Abstract

Introduction: Spatial remapping, the process of updating information across eye movements, is an important mechanism for trans-saccadic perception. The right posterior parietal cortex (PPC) is a region that has been associated most strongly with spatial remapping. The aim of the project was to investigate the effect of damage to the right PPC on direction specific trans-saccadic memory. We compared trans-saccadic memory performance for central items that had to be remembered while making a left- versus rightward eye movement, or for items that were remapped within the left versus right visual field. Methods: We included 9 stroke patients with unilateral right PPC lesions and 31 healthy control subjects. Participants memorized the location of a briefly presented item, had to make one saccade (either towards the left or right, or upward or downward), and subsequently had to decide in what direction the probe had shifted. We used a staircase to adjust task difficulty (i.e., the distance between the memory item and probe). Bayesian repeated measures ANOVAs were used to compare left versus right eye movements and items in the left versus right visual field. Results: In both conditions, patients with right PPC damage showed worse trans-saccadic memory performance compared to healthy control subjects (for the condition with left- and rightward gaze shifts, BF10 = 3.79; and when items were presented left or right, BF10 = 6.77), regardless of the direction of the gaze or the initial location of the memory item. At the individual level, none of the patients showed a direction specific deficit after leftward versus rightward saccades, whereas two patients showed worse performance for items in the left versus right visual field. Conclusion: Damage in the right PPC did not lead to gaze direction specific impairments in trans-saccadic memory, but instead caused more general spatial memory impairments.

Original languageEnglish
Pages (from-to)284-297
Number of pages14
JournalCortex
Volume120
Early online date28 Jun 2019
DOIs
Publication statusPublished - 1 Nov 2019

Keywords

  • Constructional apraxia
  • Hemispatial neglect
  • Parietal cortex
  • Spatial remapping
  • Spatial working memory

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience

Cite this

Ten Brink, A. F., Fabius, J. H., Weaver, N. A., Nijboer, T. C. W., & Van der Stigchel, S. (2019). Trans-saccadic memory after right parietal brain damage. Cortex, 120, 284-297. https://doi.org/10.1016/j.cortex.2019.06.006

Trans-saccadic memory after right parietal brain damage. / Ten Brink, Antonia F.; Fabius, Jasper H.; Weaver, Nick A.; Nijboer, Tanja C.W.; Van der Stigchel, Stefan.

In: Cortex, Vol. 120, 01.11.2019, p. 284-297.

Research output: Contribution to journalArticle

Ten Brink, AF, Fabius, JH, Weaver, NA, Nijboer, TCW & Van der Stigchel, S 2019, 'Trans-saccadic memory after right parietal brain damage', Cortex, vol. 120, pp. 284-297. https://doi.org/10.1016/j.cortex.2019.06.006
Ten Brink AF, Fabius JH, Weaver NA, Nijboer TCW, Van der Stigchel S. Trans-saccadic memory after right parietal brain damage. Cortex. 2019 Nov 1;120:284-297. https://doi.org/10.1016/j.cortex.2019.06.006
Ten Brink, Antonia F. ; Fabius, Jasper H. ; Weaver, Nick A. ; Nijboer, Tanja C.W. ; Van der Stigchel, Stefan. / Trans-saccadic memory after right parietal brain damage. In: Cortex. 2019 ; Vol. 120. pp. 284-297.
@article{85bf3b8568ae4523a594c847cb18fc45,
title = "Trans-saccadic memory after right parietal brain damage",
abstract = "Introduction: Spatial remapping, the process of updating information across eye movements, is an important mechanism for trans-saccadic perception. The right posterior parietal cortex (PPC) is a region that has been associated most strongly with spatial remapping. The aim of the project was to investigate the effect of damage to the right PPC on direction specific trans-saccadic memory. We compared trans-saccadic memory performance for central items that had to be remembered while making a left- versus rightward eye movement, or for items that were remapped within the left versus right visual field. Methods: We included 9 stroke patients with unilateral right PPC lesions and 31 healthy control subjects. Participants memorized the location of a briefly presented item, had to make one saccade (either towards the left or right, or upward or downward), and subsequently had to decide in what direction the probe had shifted. We used a staircase to adjust task difficulty (i.e., the distance between the memory item and probe). Bayesian repeated measures ANOVAs were used to compare left versus right eye movements and items in the left versus right visual field. Results: In both conditions, patients with right PPC damage showed worse trans-saccadic memory performance compared to healthy control subjects (for the condition with left- and rightward gaze shifts, BF10 = 3.79; and when items were presented left or right, BF10 = 6.77), regardless of the direction of the gaze or the initial location of the memory item. At the individual level, none of the patients showed a direction specific deficit after leftward versus rightward saccades, whereas two patients showed worse performance for items in the left versus right visual field. Conclusion: Damage in the right PPC did not lead to gaze direction specific impairments in trans-saccadic memory, but instead caused more general spatial memory impairments.",
keywords = "Constructional apraxia, Hemispatial neglect, Parietal cortex, Spatial remapping, Spatial working memory",
author = "{Ten Brink}, {Antonia F.} and Fabius, {Jasper H.} and Weaver, {Nick A.} and Nijboer, {Tanja C.W.} and {Van der Stigchel}, Stefan",
year = "2019",
month = "11",
day = "1",
doi = "10.1016/j.cortex.2019.06.006",
language = "English",
volume = "120",
pages = "284--297",
journal = "Cortex",
issn = "0010-9452",
publisher = "Masson SpA",

}

TY - JOUR

T1 - Trans-saccadic memory after right parietal brain damage

AU - Ten Brink, Antonia F.

AU - Fabius, Jasper H.

AU - Weaver, Nick A.

AU - Nijboer, Tanja C.W.

AU - Van der Stigchel, Stefan

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Introduction: Spatial remapping, the process of updating information across eye movements, is an important mechanism for trans-saccadic perception. The right posterior parietal cortex (PPC) is a region that has been associated most strongly with spatial remapping. The aim of the project was to investigate the effect of damage to the right PPC on direction specific trans-saccadic memory. We compared trans-saccadic memory performance for central items that had to be remembered while making a left- versus rightward eye movement, or for items that were remapped within the left versus right visual field. Methods: We included 9 stroke patients with unilateral right PPC lesions and 31 healthy control subjects. Participants memorized the location of a briefly presented item, had to make one saccade (either towards the left or right, or upward or downward), and subsequently had to decide in what direction the probe had shifted. We used a staircase to adjust task difficulty (i.e., the distance between the memory item and probe). Bayesian repeated measures ANOVAs were used to compare left versus right eye movements and items in the left versus right visual field. Results: In both conditions, patients with right PPC damage showed worse trans-saccadic memory performance compared to healthy control subjects (for the condition with left- and rightward gaze shifts, BF10 = 3.79; and when items were presented left or right, BF10 = 6.77), regardless of the direction of the gaze or the initial location of the memory item. At the individual level, none of the patients showed a direction specific deficit after leftward versus rightward saccades, whereas two patients showed worse performance for items in the left versus right visual field. Conclusion: Damage in the right PPC did not lead to gaze direction specific impairments in trans-saccadic memory, but instead caused more general spatial memory impairments.

AB - Introduction: Spatial remapping, the process of updating information across eye movements, is an important mechanism for trans-saccadic perception. The right posterior parietal cortex (PPC) is a region that has been associated most strongly with spatial remapping. The aim of the project was to investigate the effect of damage to the right PPC on direction specific trans-saccadic memory. We compared trans-saccadic memory performance for central items that had to be remembered while making a left- versus rightward eye movement, or for items that were remapped within the left versus right visual field. Methods: We included 9 stroke patients with unilateral right PPC lesions and 31 healthy control subjects. Participants memorized the location of a briefly presented item, had to make one saccade (either towards the left or right, or upward or downward), and subsequently had to decide in what direction the probe had shifted. We used a staircase to adjust task difficulty (i.e., the distance between the memory item and probe). Bayesian repeated measures ANOVAs were used to compare left versus right eye movements and items in the left versus right visual field. Results: In both conditions, patients with right PPC damage showed worse trans-saccadic memory performance compared to healthy control subjects (for the condition with left- and rightward gaze shifts, BF10 = 3.79; and when items were presented left or right, BF10 = 6.77), regardless of the direction of the gaze or the initial location of the memory item. At the individual level, none of the patients showed a direction specific deficit after leftward versus rightward saccades, whereas two patients showed worse performance for items in the left versus right visual field. Conclusion: Damage in the right PPC did not lead to gaze direction specific impairments in trans-saccadic memory, but instead caused more general spatial memory impairments.

KW - Constructional apraxia

KW - Hemispatial neglect

KW - Parietal cortex

KW - Spatial remapping

KW - Spatial working memory

UR - http://www.scopus.com/inward/record.url?scp=85069905337&partnerID=8YFLogxK

U2 - 10.1016/j.cortex.2019.06.006

DO - 10.1016/j.cortex.2019.06.006

M3 - Article

AN - SCOPUS:85069905337

VL - 120

SP - 284

EP - 297

JO - Cortex

JF - Cortex

SN - 0010-9452

ER -