Towards a high-precision, embedded system for versatile sensitive biosensing measurements

Konstantinos I. Papadimitriou; Ioannis Zeimpekis; Despina Moschou; Kai Sun; Chunxiao Hu; Peter Ashburn; Hywel Morgan; Themistoklis Prodromakis

doi:10.1109/BioCAS.2015.7348432

Towards a high-precision, embedded system for versatile sensitive biosensing measurements

Konstantinos I. Papadimitriou, Ioannis Zeimpekis, Despina Moschou, Kai Sun, Chunxiao Hu, Peter Ashburn, Hywel Morgan, Themistoklis Prodromakis

Department of Electronic & Electrical Engineering

University of Southampton

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

4 Citations (SciVal)

Abstract

This paper demonstrates a versatile, high-Accuracy, data-Acquisition electronic platform for biosensing measurements, capable of collecting minute current and voltage input signals, stemming from various types of amperometric and potentiometric biosensors. The instrument is able to process the incoming analog signals in a digital manner and export them back to the user either as an amplified analog signal or in digital format through a USB 2.0 interface. The proposed system comprises off-The-shelf IC components and a commercially available FPGA-based DSP unit. The performance of the instrumentation platform has been tested initially by means of very small ideal current and voltage signals generated by precise electronic equipments and subsequently has been validated via proof-of-concept experiments with amperometric and potentiometric sensors. The results shown in this paper exhibit potential for integrating specific sections of the proposed instrumentation board with appropriate biosensors, towards developing affordable, yet reliable Point-Of-Care (POC) diagnostic tools for sensitive biochemical measurements.

Original language	English
Title of host publication	IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings
Publisher	IEEE
ISBN (Electronic)	9781479972333
ISBN (Print)	9781479972333
DOIs	https://doi.org/10.1109/BioCAS.2015.7348432
Publication status	Published - 4 Dec 2015
Event	11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015 - Atlanta, USA United States Duration: 22 Oct 2015 → 24 Oct 2015

Conference

Conference	11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015
Country/Territory	USA United States
City	Atlanta
Period	22/10/15 → 24/10/15

Keywords

Analog-To-Digital Conversion
Biosensing
Data-Acquisition
Embedded System
Nanoribbon TFT
PCB-Based Sensor
Switched Capacitor

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10.1109/BioCAS.2015.7348432

Cite this

Papadimitriou, K. I., Zeimpekis, I., Moschou, D., Sun, K., Hu, C., Ashburn, P., Morgan, H., & Prodromakis, T. (2015). Towards a high-precision, embedded system for versatile sensitive biosensing measurements. In IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings Article 7348432 IEEE. https://doi.org/10.1109/BioCAS.2015.7348432

Towards a high-precision, embedded system for versatile sensitive biosensing measurements. / Papadimitriou, Konstantinos I.; Zeimpekis, Ioannis; Moschou, Despina et al.
IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings. IEEE, 2015. 7348432.

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

Papadimitriou, KI, Zeimpekis, I, Moschou, D, Sun, K, Hu, C, Ashburn, P, Morgan, H & Prodromakis, T 2015, Towards a high-precision, embedded system for versatile sensitive biosensing measurements. in IEEE Biomedical Circuits and Systems Conference: Engineering for Healthy Minds and Able Bodies, BioCAS 2015 - Proceedings., 7348432, IEEE, 11th IEEE Biomedical Circuits and Systems Conference, BioCAS 2015, Atlanta, USA United States, 22/10/15. https://doi.org/10.1109/BioCAS.2015.7348432

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abstract = "This paper demonstrates a versatile, high-Accuracy, data-Acquisition electronic platform for biosensing measurements, capable of collecting minute current and voltage input signals, stemming from various types of amperometric and potentiometric biosensors. The instrument is able to process the incoming analog signals in a digital manner and export them back to the user either as an amplified analog signal or in digital format through a USB 2.0 interface. The proposed system comprises off-The-shelf IC components and a commercially available FPGA-based DSP unit. The performance of the instrumentation platform has been tested initially by means of very small ideal current and voltage signals generated by precise electronic equipments and subsequently has been validated via proof-of-concept experiments with amperometric and potentiometric sensors. The results shown in this paper exhibit potential for integrating specific sections of the proposed instrumentation board with appropriate biosensors, towards developing affordable, yet reliable Point-Of-Care (POC) diagnostic tools for sensitive biochemical measurements.",

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AU - Hu, Chunxiao

AU - Ashburn, Peter

AU - Morgan, Hywel

AU - Prodromakis, Themistoklis

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N2 - This paper demonstrates a versatile, high-Accuracy, data-Acquisition electronic platform for biosensing measurements, capable of collecting minute current and voltage input signals, stemming from various types of amperometric and potentiometric biosensors. The instrument is able to process the incoming analog signals in a digital manner and export them back to the user either as an amplified analog signal or in digital format through a USB 2.0 interface. The proposed system comprises off-The-shelf IC components and a commercially available FPGA-based DSP unit. The performance of the instrumentation platform has been tested initially by means of very small ideal current and voltage signals generated by precise electronic equipments and subsequently has been validated via proof-of-concept experiments with amperometric and potentiometric sensors. The results shown in this paper exhibit potential for integrating specific sections of the proposed instrumentation board with appropriate biosensors, towards developing affordable, yet reliable Point-Of-Care (POC) diagnostic tools for sensitive biochemical measurements.

AB - This paper demonstrates a versatile, high-Accuracy, data-Acquisition electronic platform for biosensing measurements, capable of collecting minute current and voltage input signals, stemming from various types of amperometric and potentiometric biosensors. The instrument is able to process the incoming analog signals in a digital manner and export them back to the user either as an amplified analog signal or in digital format through a USB 2.0 interface. The proposed system comprises off-The-shelf IC components and a commercially available FPGA-based DSP unit. The performance of the instrumentation platform has been tested initially by means of very small ideal current and voltage signals generated by precise electronic equipments and subsequently has been validated via proof-of-concept experiments with amperometric and potentiometric sensors. The results shown in this paper exhibit potential for integrating specific sections of the proposed instrumentation board with appropriate biosensors, towards developing affordable, yet reliable Point-Of-Care (POC) diagnostic tools for sensitive biochemical measurements.

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Towards a high-precision, embedded system for versatile sensitive biosensing measurements

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Keywords

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