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The tri-molecular concept: exploiting the lipid membrane in the design of potent and selective inhibitors for voltage-gated sodium channels
Akello Agwa
Department of Life Sciences
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Doctoral Thesis
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Dive into the research topics of 'The tri-molecular concept: exploiting the lipid membrane in the design of potent and selective inhibitors for voltage-gated sodium channels'. Together they form a unique fingerprint.
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Biochemistry, Genetics and Molecular Biology
Lipid Bilayer
100%
Membrane Lipid
100%
Electric Potential
100%
Sodium Channel
100%
Nav1.7
75%
Voltage-Gated Channel
50%
Disulfide
25%
Pharmacophore
25%
Artificial Membrane
25%
Sodium Channel Pharmacology
25%
Enzyme
12%
Solution and Solubility
12%
Amino Acids
12%
Binding Affinity
12%
Cystine Knot Motif
12%
Static Electricity
12%
Surface Plasmon Resonance
12%
Oxidative Folding
12%
Membrane Binding
12%
Sortase A
12%
Inhibitor Cystine Knot
12%
Scorpion
12%
Fluorescence Spectroscopy
12%
Tryptophan
12%