The rise and fall of deleterious mutation

K J Balbi; E J Feil

doi:10.1016/j.resmic.2007.09.005

The rise and fall of deleterious mutation

K J Balbi, E J Feil

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

21 Citations (SciVal)

Abstract

It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.

Original language	English
Pages (from-to)	779-786
Number of pages	8
Journal	Research in Microbiology
Volume	158
Issue number	10
DOIs	https://doi.org/10.1016/j.resmic.2007.09.005
Publication status	Published - 2007

Bibliographical note

ID number: ISI:000252370300007

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10.1016/j.resmic.2007.09.005

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abstract = "It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.",

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AB - It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.

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DO - 10.1016/j.resmic.2007.09.005

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JO - Research in Microbiology

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The rise and fall of deleterious mutation

Abstract

Bibliographical note

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