The rise and fall of deleterious mutation

K J Balbi, E J Feil

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.
Original languageEnglish
Pages (from-to)779-786
Number of pages8
JournalResearch in Microbiology
Volume158
Issue number10
DOIs
Publication statusPublished - 2007

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