The rise and fall of deleterious mutation

K J Balbi, E J Feil

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21 Citations (SciVal)


It is well established that selection is less efficient in small populations than in large ones. Here we review the impact of this effect by considering the gradual selective purging of deleterious mutation over time. We Outline an approach to explore the dynamics of this process, and highlight its profound implications. (c) 2007 Elsevier Masson SAS. All rights reserved.
Original languageEnglish
Pages (from-to)779-786
Number of pages8
JournalResearch in Microbiology
Issue number10
Publication statusPublished - 2007

Bibliographical note

ID number: ISI:000252370300007


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