The rhodium-catalysed 1,2-addition of arylboronic acids to aldehydes and ketones with sulfonated S-Phos

J.R. White, G.J. Price, P.K. Plucinski, C.G. Frost

Research output: Contribution to journalArticlepeer-review

27 Citations (Scopus)

Abstract

The rhodium-catalysed 1,2-addition of arylboronic acids to aryl aldehydes has been accomplished in high yield using sulfonated S-Phos, a water-soluble biaryl phosphine ligand which allows for catalyst recycling. The catalytic protocol has also been successful in the challenging arylation of ketones.
Original languageEnglish
Pages (from-to)7365-7368
Number of pages4
JournalTetrahedron Letters
Volume50
Issue number52
DOIs
Publication statusPublished - 30 Dec 2009

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