TY - JOUR
T1 - The reduction of functionalized pyrazolium salts as a stereoselective route to functionalized pyrazolidines
AU - Bañuelos, Luis A.
AU - Cuadrado, Purificación
AU - González-Nogal, Ana M.
AU - López-Solera, Isabel
AU - Pulido, Francisco J.
AU - Raithby, Paul R.
PY - 1996/7/1
Y1 - 1996/7/1
N2 - Functionalized pyrazolium salts 1 react with metal complex hydrides (LiAlH4 and NaBH4) to give pyrazolidines 2 with good-to-excellent levels of diastereoselectivity. The stereochemical course of the reduction is essentially anti, leading to trans-trans-pyrazolidines. The relative configuration of the crystalline pyrazolidine 2c has been determined by X-ray crystallographic analysis.
AB - Functionalized pyrazolium salts 1 react with metal complex hydrides (LiAlH4 and NaBH4) to give pyrazolidines 2 with good-to-excellent levels of diastereoselectivity. The stereochemical course of the reduction is essentially anti, leading to trans-trans-pyrazolidines. The relative configuration of the crystalline pyrazolidine 2c has been determined by X-ray crystallographic analysis.
UR - http://www.scopus.com/inward/record.url?scp=0030199701&partnerID=8YFLogxK
U2 - 10.1016/0040-4020(96)00470-X
DO - 10.1016/0040-4020(96)00470-X
M3 - Article
AN - SCOPUS:0030199701
SN - 0040-4020
VL - 52
SP - 9193
EP - 9206
JO - Tetrahedron
JF - Tetrahedron
IS - 27
ER -