The preparation of functionalised aryl phosphines from aryl fluorides by nucleophilic aromatic substitution with potassium diphenylphosphide

Steven J. Coote; Graham J. Dawson; Christopher G. Frost; Jonathan M.J. Williams

doi:10.1055/s-1993-22510

The preparation of functionalised aryl phosphines from aryl fluorides by nucleophilic aromatic substitution with potassium diphenylphosphide

Steven J. Coote
, Graham J. Dawson
, Christopher G. Frost
, Jonathan M.J. Williams

GlaxoSmithKline
Loughborough University

Research output: Contribution to journal › Article › peer-review

Abstract

The reaction of o-substituted aryl fluorides with potassium diphenylphosphide affords the corresponding o-substituted aryl phosphines by nucleophilic aromatic substitution in 72-96% yield. The products have wide application as ligands and ligand precursors.

Original language	English
Pages (from-to)	509-510
Number of pages	2
Journal	Synlett
Volume	1993
Issue number	7
DOIs	https://doi.org/10.1055/s-1993-22510
Publication status	Published - 1 Jul 1993

ASJC Scopus subject areas

Organic Chemistry

Access to Document

10.1055/s-1993-22510

Cite this

@article{ecc1a76c17d047c5b29b8579b206daee,

title = "The preparation of functionalised aryl phosphines from aryl fluorides by nucleophilic aromatic substitution with potassium diphenylphosphide",

abstract = "The reaction of o-substituted aryl fluorides with potassium diphenylphosphide affords the corresponding o-substituted aryl phosphines by nucleophilic aromatic substitution in 72-96\% yield. The products have wide application as ligands and ligand precursors.",

author = "Coote, \{Steven J.\} and Dawson, \{Graham J.\} and Frost, \{Christopher G.\} and Williams, \{Jonathan M.J.\}",

year = "1993",

month = jul,

day = "1",

doi = "10.1055/s-1993-22510",

language = "English",

volume = "1993",

pages = "509--510",

journal = "Synlett",

issn = "0936-5214",

publisher = "Georg Thieme Verlag",

number = "7",

}

TY - JOUR

T1 - The preparation of functionalised aryl phosphines from aryl fluorides by nucleophilic aromatic substitution with potassium diphenylphosphide

AU - Coote, Steven J.

AU - Dawson, Graham J.

AU - Frost, Christopher G.

AU - Williams, Jonathan M.J.

PY - 1993/7/1

Y1 - 1993/7/1

N2 - The reaction of o-substituted aryl fluorides with potassium diphenylphosphide affords the corresponding o-substituted aryl phosphines by nucleophilic aromatic substitution in 72-96% yield. The products have wide application as ligands and ligand precursors.

AB - The reaction of o-substituted aryl fluorides with potassium diphenylphosphide affords the corresponding o-substituted aryl phosphines by nucleophilic aromatic substitution in 72-96% yield. The products have wide application as ligands and ligand precursors.

UR - https://www.scopus.com/pages/publications/84987181592

U2 - 10.1055/s-1993-22510

DO - 10.1055/s-1993-22510

M3 - Article

AN - SCOPUS:84987181592

SN - 0936-5214

VL - 1993

SP - 509

EP - 510

JO - Synlett

JF - Synlett

IS - 7

ER -

The preparation of functionalised aryl phosphines from aryl fluorides by nucleophilic aromatic substitution with potassium diphenylphosphide

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this