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As 3D printers become more widely available, researchers are able to rapidly produce components that may have previously taken weeks to have machined. The resulting plastic components, having high surface roughness, are often not suitable for high-precision optomechanics. However, by playing to the strengths of 3D printing—namely the ability toprint complex internal geometries—it is possible to design monolithic mechanisms that do not rely on tight integration of high-precision parts. Here we present a motorised monolithic3D-printed plastic flexure stage with sub-100 nm resolution, that can perform automated optical fibre alignment.