The microbial production of epoxides

David J. Leak; Peter J. Aikens; Mahmoud Seyed-Mahmoudian

doi:10.1016/0167-7799(92)90234-M

The microbial production of epoxides

David J. Leak, Peter J. Aikens, Mahmoud Seyed-Mahmoudian

Research output: Contribution to journal › Review article › peer-review

Abstract

Chiral compounds in which biological activity resides in only one of the enantiomers are, increasingly, being demanded in enantiomerically pure form. The use of biocatalysts for production of epoxides as chiral intermediates in the synthesis of these compounds has realistic commercial prospects, but also presents formidable technical problems.

Original language	English
Pages (from-to)	256-261
Number of pages	6
Journal	Trends in Biotechnology
Volume	10
Issue number	C
DOIs	https://doi.org/10.1016/0167-7799(92)90234-M
Publication status	Published - 1 Jan 1992

Funding

The financial and technical support of work on direct epoxidation (ICI Bioproducts and SERC) and kinetic resolution (CEC and Andeno/DSM) is gratefully acknowledged.

ASJC Scopus subject areas

Biotechnology
Bioengineering

Access to Document

10.1016/0167-7799(92)90234-M

Cite this

@article{f1b4a3d07dec4b8a880fb00b23c66136,

title = "The microbial production of epoxides",

abstract = "Chiral compounds in which biological activity resides in only one of the enantiomers are, increasingly, being demanded in enantiomerically pure form. The use of biocatalysts for production of epoxides as chiral intermediates in the synthesis of these compounds has realistic commercial prospects, but also presents formidable technical problems.",

author = "Leak, {David J.} and Aikens, {Peter J.} and Mahmoud Seyed-Mahmoudian",

year = "1992",

month = jan,

day = "1",

doi = "10.1016/0167-7799(92)90234-M",

language = "English",

volume = "10",

pages = "256--261",

journal = "Trends in Biotechnology",

issn = "0167-7799",

publisher = "Elsevier",

number = "C",

}

TY - JOUR

T1 - The microbial production of epoxides

AU - Leak, David J.

AU - Aikens, Peter J.

AU - Seyed-Mahmoudian, Mahmoud

PY - 1992/1/1

Y1 - 1992/1/1

N2 - Chiral compounds in which biological activity resides in only one of the enantiomers are, increasingly, being demanded in enantiomerically pure form. The use of biocatalysts for production of epoxides as chiral intermediates in the synthesis of these compounds has realistic commercial prospects, but also presents formidable technical problems.

AB - Chiral compounds in which biological activity resides in only one of the enantiomers are, increasingly, being demanded in enantiomerically pure form. The use of biocatalysts for production of epoxides as chiral intermediates in the synthesis of these compounds has realistic commercial prospects, but also presents formidable technical problems.

UR - http://www.scopus.com/inward/record.url?scp=0026710288&partnerID=8YFLogxK

U2 - 10.1016/0167-7799(92)90234-M

DO - 10.1016/0167-7799(92)90234-M

M3 - Review article

AN - SCOPUS:0026710288

SN - 0167-7799

VL - 10

SP - 256

EP - 261

JO - Trends in Biotechnology

JF - Trends in Biotechnology

IS - C

ER -

The microbial production of epoxides

Abstract

Funding

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this