The microbial production of epoxides

David J. Leak, Peter J. Aikens, Mahmoud Seyed-Mahmoudian

Research output: Contribution to journalReview articlepeer-review

Abstract

Chiral compounds in which biological activity resides in only one of the enantiomers are, increasingly, being demanded in enantiomerically pure form. The use of biocatalysts for production of epoxides as chiral intermediates in the synthesis of these compounds has realistic commercial prospects, but also presents formidable technical problems.

Original languageEnglish
Pages (from-to)256-261
Number of pages6
JournalTrends in Biotechnology
Volume10
Issue numberC
DOIs
Publication statusPublished - 1 Jan 1992

Funding

The financial and technical support of work on direct epoxidation (ICI Bioproducts and SERC) and kinetic resolution (CEC and Andeno/DSM) is gratefully acknowledged.

ASJC Scopus subject areas

  • Biotechnology
  • Bioengineering

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