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The mechanisms by which a whole-school intervention might improve sexual health: qualitative realist research nested in a trial in English secondary schools

  • Ruth Ponsford
  • , Rebecca Meiksin
  • , Veena Muraleetharan
  • , Nerissa Tilouche
  • , G.J. Melendez-Torres
  • , Josephine McAllister
  • , Maria Lohan
  • , Alison Hadley
  • , Honor Young
  • , Rona Campbell
  • , Catherine Mercer
  • , Karin Coyle
  • , Jo Sturgess
  • , Charles Opondo
  • , Steve Morris
  • , Elizabeth Allen
  • , Chris Bonell
  • London School of Hygiene & Tropical Medicine
  • University of Exeter
  • Queen's University Belfast
  • Hitotsubashi University
  • University of Bedfordshire
  • Cardiff University
  • Bristol Medical School, University of Bristol
  • University College London
  • ATR Associates
  • University of Cambridge

Research output: Contribution to journal › Article › peer-review

Abstract

Whole-school interventions go beyond classroom education, promoting health by modifying school environments. These can be effective in delaying sexual debut and increasing contraception use but mechanisms are poorly understood. Qualitative research within realist evaluation can explore mechanisms via building ‘context-mechanism-outcome configurations’, describing how interventions trigger mechanisms that interact with context to generate outcomes. We explored these for the Positive Choices whole-school sexual health intervention within the intervention arm of a randomised trial conducted 2021–2025. Using ‘dimensional analysis’, we analysed 52 interviews with teachers and 40 focus-groups involving 266 students from 22 English secondary schools. Our results suggest seven mechanisms through which whole-school interventions might ‘work’: improving knowledge using diverse pedagogies; improving confidence and ability to talk by normalising talk about sexual health; changing gender attitudes through challenging stereotypes and providing insights and empathy with others' perspectives; promoting access to sexual health and other services via helping students understand their needs and entitlements; building school engagement by providing new student roles on decision-making groups; increasing inclusion of sexual-minority students by normalising consideration of non-heterosexual identities and practices; and reducing sexual harassment and abuse by helping students understand consent and when to intervene in harassment. Contextual contingencies included: high initial student needs; teacher skills and commitment; and school commitment and capacity. Our research suggests novel mechanisms via which whole-school interventions might promote sexual health. Quantitative analyses will now be conducted to examine these mechanisms and contingencies.
Original languageEnglish
Article number118461
JournalSocial Science & Medicine
Volume388
Early online date7 Nov 2025
DOIs
Publication statusPublished - 31 Jan 2026

Data Availability Statement

Data will be made available on request.

Acknowledgements

We thank the staff and students of participating schools for their time and commitment. We thank Lucy Emmerson and Rachael Baker of the Sex Education Forum for leading the intervention. We thank Despoina Xenikaki for her administrative support. We thank the fieldwork team for their work on the surveys.

Funding

This study was funded by the National Institute for Health Research in England under its Public Health Research Board (131487). Prof G.J. Melendez-Torres is an NIHR Senior Investigator. The views expressed in this publication are those of the authors and do not necessarily reflect those of the UK NHS, the National Institute for Health Research or the Department of Health for England. We thank the staff and students of participating schools for their time and commitment. We thank Lucy Emmerson and Rachael Baker of the Sex Education Forum for leading the intervention. We thank Despoina Xenikaki for her administrative support. We thank the fieldwork team for their work on the surveys. This study was funded by the National Institute for Health Research in England under its Public Health Research Board (131487). Prof G.J. Melendez-Torres is an NIHR Senior Investigator. The views expressed in this publication are those of the authors and do not necessarily reflect those of the UK NHS, the National Institute for Health Research or the Department of Health for England.

FundersFunder number
National Institute on Handicapped Research
National Institute for Health and Care Research
Department of Health for England
National Institute for Health Research in England
Public Health Research Board131487

    Keywords

    • School
    • Sex education
    • Adolescent
    • Sexual health
    • Mechanisms
    • Realist evaluation
    • Qualitative research

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