The Hows and Whys

Laurence D. Hurst, Csaba Pál

Research output: Contribution to journalArticlepeer-review

Abstract

In the majority of organisms, most gene knockouts have little or no affect on viability. Does this mean that most genes are dispensable to an organism? What are the underlying mechanisms of dispensability and why did dispensability evolve?

Original languageEnglish
Pages (from-to)30-34
Number of pages5
JournalThe Biochemist
Volume31
Issue number1
DOIs
Publication statusPublished - 1 Feb 2009

Keywords

  • enzymes
  • gene knockouts
  • isozymes
  • mutation rates
  • paralogs

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Cite this