The genetic sex-determination system predicts adult sex ratios in tetrapods

Ivett Pipoly; Veronika Bókony; Mark Kirkpatrick; Paul F. Donald; Tamás Székely; András Liker

doi:10.1038/nature15380

The genetic sex-determination system predicts adult sex ratios in tetrapods

Ivett Pipoly, Veronika Bókony, Mark Kirkpatrick, Paul F. Donald, Tamás Székely, András Liker

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Abstract

The adult sex ratio (ASR) has critical effects on behaviour, ecology and population dynamics, but the causes of variation in ASRs are unclear. Here we assess whether the type of genetic sex determination influences the ASR using data from 344 species in 117 families of tetrapods. We show that taxa with female heterogamety have a significantly more male-biased ASR (proportion of males: 0.55 ± 0.01 (mean ± s.e.m.)) than taxa with male heterogamety (0.43 ± 0.01). The genetic sex-determination system explains 24% of interspecific variation in ASRs in amphibians and 36% in reptiles. We consider several genetic factors that could contribute to this pattern, including meiotic drive and sex-linked deleterious mutations, but further work is needed to quantify their effects. Regardless of the mechanism, the effects of the genetic sex-determination system on the adult sex ratio are likely to have profound effects on the demography and social behaviour of tetrapods.

Original language	English
Pages (from-to)	91-94
Number of pages	4
Journal	Nature
Volume	527
Issue number	7576
Early online date	7 Oct 2015
DOIs	https://doi.org/10.1038/nature15380
Publication status	Published - 5 Nov 2015

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Tamas Szekely
- T.Szekelybath.acuk
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title = "The genetic sex-determination system predicts adult sex ratios in tetrapods",

abstract = "The adult sex ratio (ASR) has critical effects on behaviour, ecology and population dynamics, but the causes of variation in ASRs are unclear. Here we assess whether the type of genetic sex determination influences the ASR using data from 344 species in 117 families of tetrapods. We show that taxa with female heterogamety have a significantly more male-biased ASR (proportion of males: 0.55 ± 0.01 (mean ± s.e.m.)) than taxa with male heterogamety (0.43 ± 0.01). The genetic sex-determination system explains 24% of interspecific variation in ASRs in amphibians and 36% in reptiles. We consider several genetic factors that could contribute to this pattern, including meiotic drive and sex-linked deleterious mutations, but further work is needed to quantify their effects. Regardless of the mechanism, the effects of the genetic sex-determination system on the adult sex ratio are likely to have profound effects on the demography and social behaviour of tetrapods.",

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AU - Pipoly, Ivett

AU - Bókony, Veronika

AU - Kirkpatrick, Mark

AU - Donald, Paul F.

AU - Székely, Tamás

AU - Liker, András

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AB - The adult sex ratio (ASR) has critical effects on behaviour, ecology and population dynamics, but the causes of variation in ASRs are unclear. Here we assess whether the type of genetic sex determination influences the ASR using data from 344 species in 117 families of tetrapods. We show that taxa with female heterogamety have a significantly more male-biased ASR (proportion of males: 0.55 ± 0.01 (mean ± s.e.m.)) than taxa with male heterogamety (0.43 ± 0.01). The genetic sex-determination system explains 24% of interspecific variation in ASRs in amphibians and 36% in reptiles. We consider several genetic factors that could contribute to this pattern, including meiotic drive and sex-linked deleterious mutations, but further work is needed to quantify their effects. Regardless of the mechanism, the effects of the genetic sex-determination system on the adult sex ratio are likely to have profound effects on the demography and social behaviour of tetrapods.

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The genetic sex-determination system predicts adult sex ratios in tetrapods

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Tamas Szekely

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