The form of a trade-off determines the response to competition

R. Maharjan, S. Nilsson, J. Sung, K. Haynes, R.E. Beardmore, L.D. Hurst, T. Ferenci, I. Gudelj

Research output: Contribution to journalArticle

32 Citations (Scopus)

Abstract

Understanding how populations and communities respond to competition is a central concern of ecology. A seminal theoretical solution first formalised by Levins (and re-derived in multiple fields) showed that, in theory, the form of a trade-off should determine the outcome of competition. While this has become a central postulate in ecology it has evaded experimental verification, not least because of substantial technical obstacles. We here solve the experimental problems by employing synthetic ecology. We engineer strains of Escherichia coli with fixed resource allocations enabling accurate measurement of trade-off shapes between bacterial survival and multiplication in multiple environments. A mathematical chemostat model predicts different, and experimentally verified, trajectories of gene frequency changes as a function of condition-specific trade-offs. The results support Levins' postulate and demonstrates that otherwise paradoxical alternative outcomes witnessed in subtly different conditions are predictable.
Original languageEnglish
Pages (from-to)1267-1276
Number of pages10
JournalEcology Letters
Volume16
Issue number10
Early online date31 Jul 2013
DOIs
Publication statusPublished - Oct 2013

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trade-off
ecology
chemostat
resource allocation
engineers
trajectories
gene frequency
mathematical models
trajectory
Escherichia coli
gene

Cite this

Maharjan, R., Nilsson, S., Sung, J., Haynes, K., Beardmore, R. E., Hurst, L. D., ... Gudelj, I. (2013). The form of a trade-off determines the response to competition. Ecology Letters, 16(10), 1267-1276. https://doi.org/10.1111/ele.12159

The form of a trade-off determines the response to competition. / Maharjan, R.; Nilsson, S.; Sung, J.; Haynes, K.; Beardmore, R.E.; Hurst, L.D.; Ferenci, T.; Gudelj, I.

In: Ecology Letters, Vol. 16, No. 10, 10.2013, p. 1267-1276.

Research output: Contribution to journalArticle

Maharjan, R, Nilsson, S, Sung, J, Haynes, K, Beardmore, RE, Hurst, LD, Ferenci, T & Gudelj, I 2013, 'The form of a trade-off determines the response to competition', Ecology Letters, vol. 16, no. 10, pp. 1267-1276. https://doi.org/10.1111/ele.12159
Maharjan R, Nilsson S, Sung J, Haynes K, Beardmore RE, Hurst LD et al. The form of a trade-off determines the response to competition. Ecology Letters. 2013 Oct;16(10):1267-1276. https://doi.org/10.1111/ele.12159
Maharjan, R. ; Nilsson, S. ; Sung, J. ; Haynes, K. ; Beardmore, R.E. ; Hurst, L.D. ; Ferenci, T. ; Gudelj, I. / The form of a trade-off determines the response to competition. In: Ecology Letters. 2013 ; Vol. 16, No. 10. pp. 1267-1276.
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