The Emerging Roles of Cytosine-5 Methylation in mRNAs

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Recent studies have unequivocally confirmed the presence of 5-methylcytosine (m5C) in mammalian mRNAs while indicating significant functional roles for this internal base modification type. Here, a brief history of m5C epitranscriptome research and a discussion of the important ways in which the field may now progress is presented.

Original languageEnglish
Pages (from-to)498-500
Number of pages3
JournalTrends in Genetics
Issue number6
Early online date20 Feb 2021
Publication statusPublished - 1 Jun 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Ltd

Copyright 2021 Elsevier B.V., All rights reserved.


  • 5-methylcytosine
  • epitranscriptome
  • epitranscriptomics
  • m5C
  • NSun2
  • NSun6

ASJC Scopus subject areas

  • Genetics


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