The Emerging Roles of Cytosine-5 Methylation in mRNAs

Shobbir Hussain

doi:10.1016/j.tig.2021.02.001

The Emerging Roles of Cytosine-5 Methylation in mRNAs

Shobbir Hussain

Department of Life Sciences

Research output: Contribution to journal › Comment/debate › peer-review

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Abstract

Recent studies have unequivocally confirmed the presence of 5-methylcytosine (m5C) in mammalian mRNAs while indicating significant functional roles for this internal base modification type. Here, a brief history of m5C epitranscriptome research and a discussion of the important ways in which the field may now progress is presented.

Original language	English
Pages (from-to)	498-500
Number of pages	3
Journal	Trends in Genetics
Volume	37
Issue number	6
Early online date	20 Feb 2021
DOIs	https://doi.org/10.1016/j.tig.2021.02.001
Publication status	Published - 1 Jun 2021

Keywords

5-methylcytosine
epitranscriptome
epitranscriptomics
m5C
NSun2
NSun6

ASJC Scopus subject areas

Genetics

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10.1016/j.tig.2021.02.001

Manuscript_TiGAccepted author manuscript, 127 KBLicence: CC BY-NC-ND

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title = "The Emerging Roles of Cytosine-5 Methylation in mRNAs",

abstract = "Recent studies have unequivocally confirmed the presence of 5-methylcytosine (m5C) in mammalian mRNAs while indicating significant functional roles for this internal base modification type. Here, a brief history of m5C epitranscriptome research and a discussion of the important ways in which the field may now progress is presented.",

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AB - Recent studies have unequivocally confirmed the presence of 5-methylcytosine (m5C) in mammalian mRNAs while indicating significant functional roles for this internal base modification type. Here, a brief history of m5C epitranscriptome research and a discussion of the important ways in which the field may now progress is presented.

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KW - epitranscriptomics

KW - m5C

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KW - NSun6

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M3 - Comment/debate

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JO - Trends in Genetics

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The Emerging Roles of Cytosine-5 Methylation in mRNAs

Abstract

Keywords

ASJC Scopus subject areas

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Characterising the Epitanscriptome Using Catalysis-Dependent RIPseq Approaches

Cite this

The Emerging Roles of Cytosine-5 Methylation in mRNAs

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Projects

Characterising the Epitanscriptome Using Catalysis-Dependent RIPseq Approaches

Cite this