Abstract
Recent studies have unequivocally confirmed the presence of 5-methylcytosine (m5C) in mammalian mRNAs while indicating significant functional roles for this internal base modification type. Here, a brief history of m5C epitranscriptome research and a discussion of the important ways in which the field may now progress is presented.
Original language | English |
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Journal | Trends in Genetics |
DOIs | |
Publication status | E-pub ahead of print - 20 Feb 2021 |
Keywords
- 5-methylcytosine
- epitranscriptome
- epitranscriptomics
- m5C
- NSun2
- NSun6
ASJC Scopus subject areas
- Genetics