The Emerging Roles of Cytosine-5 Methylation in mRNAs

Research output: Contribution to journalShort surveypeer-review


Recent studies have unequivocally confirmed the presence of 5-methylcytosine (m5C) in mammalian mRNAs while indicating significant functional roles for this internal base modification type. Here, a brief history of m5C epitranscriptome research and a discussion of the important ways in which the field may now progress is presented.

Original languageEnglish
JournalTrends in Genetics
Publication statusE-pub ahead of print - 20 Feb 2021


  • 5-methylcytosine
  • epitranscriptome
  • epitranscriptomics
  • m5C
  • NSun2
  • NSun6

ASJC Scopus subject areas

  • Genetics

Cite this