The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes

L Rose; A T A Jenkins

doi:10.1016/j.bioelechem.2006.05.009

The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes

L Rose, A T A Jenkins

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

67 Citations (SciVal)

Abstract

Self assembled monolayers and bilayers are produced on a flat glass surface, bound by a thiolipid onto bare gold. 1,2-Dipalmitoyi-sn-Glycero-3-Phosphothioethanol (DPPTE) is used as the molecule binding to the electrode surface. The lipid lambda-alpha-Phosphatidyi-Choline-beta-Oleoyl-g-Palmiloyl (POPC) and the lipid mixture eggphosphatadiylcholine (EPC) are used as spacer lipids with the aim of achieving solid-supported artificial lipid membranes. With the aim of creating and investigating more natural systems, ion carrier proteins such as valinomycin are introduced into the DPPTE/EPC system. The direct influence on the membranes as well as the effects of different ionic solutions on the proteins is shown. (c) 2006 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	387-393
Number of pages	7
Journal	Bioelectrochemistry
Volume	70
Issue number	2
DOIs	https://doi.org/10.1016/j.bioelechem.2006.05.009
Publication status	Published - 2007

Bibliographical note

ID number: ISI:000246254500029

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10.1016/j.bioelechem.2006.05.009

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title = "The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes",

abstract = "Self assembled monolayers and bilayers are produced on a flat glass surface, bound by a thiolipid onto bare gold. 1,2-Dipalmitoyi-sn-Glycero-3-Phosphothioethanol (DPPTE) is used as the molecule binding to the electrode surface. The lipid lambda-alpha-Phosphatidyi-Choline-beta-Oleoyl-g-Palmiloyl (POPC) and the lipid mixture eggphosphatadiylcholine (EPC) are used as spacer lipids with the aim of achieving solid-supported artificial lipid membranes. With the aim of creating and investigating more natural systems, ion carrier proteins such as valinomycin are introduced into the DPPTE/EPC system. The direct influence on the membranes as well as the effects of different ionic solutions on the proteins is shown. (c) 2006 Elsevier B.V. All rights reserved.",

author = "L Rose and Jenkins, {A T A}",

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year = "2007",

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language = "English",

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T1 - The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes

AU - Rose, L

AU - Jenkins, A T A

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PY - 2007

Y1 - 2007

N2 - Self assembled monolayers and bilayers are produced on a flat glass surface, bound by a thiolipid onto bare gold. 1,2-Dipalmitoyi-sn-Glycero-3-Phosphothioethanol (DPPTE) is used as the molecule binding to the electrode surface. The lipid lambda-alpha-Phosphatidyi-Choline-beta-Oleoyl-g-Palmiloyl (POPC) and the lipid mixture eggphosphatadiylcholine (EPC) are used as spacer lipids with the aim of achieving solid-supported artificial lipid membranes. With the aim of creating and investigating more natural systems, ion carrier proteins such as valinomycin are introduced into the DPPTE/EPC system. The direct influence on the membranes as well as the effects of different ionic solutions on the proteins is shown. (c) 2006 Elsevier B.V. All rights reserved.

AB - Self assembled monolayers and bilayers are produced on a flat glass surface, bound by a thiolipid onto bare gold. 1,2-Dipalmitoyi-sn-Glycero-3-Phosphothioethanol (DPPTE) is used as the molecule binding to the electrode surface. The lipid lambda-alpha-Phosphatidyi-Choline-beta-Oleoyl-g-Palmiloyl (POPC) and the lipid mixture eggphosphatadiylcholine (EPC) are used as spacer lipids with the aim of achieving solid-supported artificial lipid membranes. With the aim of creating and investigating more natural systems, ion carrier proteins such as valinomycin are introduced into the DPPTE/EPC system. The direct influence on the membranes as well as the effects of different ionic solutions on the proteins is shown. (c) 2006 Elsevier B.V. All rights reserved.

U2 - 10.1016/j.bioelechem.2006.05.009

DO - 10.1016/j.bioelechem.2006.05.009

M3 - Article

SN - 1567-5394

VL - 70

SP - 387

EP - 393

JO - Bioelectrochemistry

JF - Bioelectrochemistry

IS - 2

ER -

The effect of the ionophore valinomycin on biomimetic solid supported lipid DPPTE/EPC membranes

Abstract

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