The colon as a site for drug delivery

Randall J. Mrsny

doi:10.1016/0168-3659(92)90113-6

The colon as a site for drug delivery

Research output: Contribution to journal › Article › peer-review

Abstract

Colonic drug absorption, as an alternative to parenteral drug delivery, is evaluated for its potential advantages and limitations. Methodologies for studying and enhancing colonic drug absorption are discussed with emphasis on the biological and chemical nature of absorption barriers. Recent efforts at identifying factors that control colonie drug absorption and which might be exploited in a delivery scheme are described.

Original language	English
Pages (from-to)	15-34
Number of pages	20
Journal	Journal of Controlled Release
Volume	22
Issue number	1
DOIs	https://doi.org/10.1016/0168-3659(92)90113-6
Publication status	Published - 1 Sept 1992

Keywords

Colon
Drug absorption
Drug delivery
Enhancer
Epithelium

ASJC Scopus subject areas

Pharmaceutical Science

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10.1016/0168-3659(92)90113-6

Cite this

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title = "The colon as a site for drug delivery",

abstract = "Colonic drug absorption, as an alternative to parenteral drug delivery, is evaluated for its potential advantages and limitations. Methodologies for studying and enhancing colonic drug absorption are discussed with emphasis on the biological and chemical nature of absorption barriers. Recent efforts at identifying factors that control colonie drug absorption and which might be exploited in a delivery scheme are described.",

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AB - Colonic drug absorption, as an alternative to parenteral drug delivery, is evaluated for its potential advantages and limitations. Methodologies for studying and enhancing colonic drug absorption are discussed with emphasis on the biological and chemical nature of absorption barriers. Recent efforts at identifying factors that control colonie drug absorption and which might be exploited in a delivery scheme are described.

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KW - Epithelium

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The colon as a site for drug delivery

Abstract

Keywords

ASJC Scopus subject areas

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