Templated dynamic synthesis of a [3]catenane

Fabien B L Cougnon, Nicholas A Jenkins, G Dan Pantoș, Jeremy K M Sanders

Research output: Contribution to journalArticle

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Abstract

The self-assembly of a water-soluble [3]catenane from a library composed of two linear building blocks, both terminated by cysteine components, is promoted either by a high salt concentration or by the presence of spermine. The spermine-templated synthesis of the [3]catenane shows that such structures can exhibit strong binding interactions with a biologically relevant target in water under near-physiological conditions.
LanguageEnglish
Pages1443-1447
Number of pages5
JournalAngewandte Chemie-International Edition
Volume51
Issue number6
DOIs
StatusPublished - 6 Feb 2012

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Spermine
Water
Libraries
Cysteine
Salts
catenane

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Cougnon, F. B. L., Jenkins, N. A., Pantoș, G. D., & Sanders, J. K. M. (2012). Templated dynamic synthesis of a [3]catenane. DOI: 10.1002/anie.201106885

Templated dynamic synthesis of a [3]catenane. / Cougnon, Fabien B L; Jenkins, Nicholas A; Pantoș, G Dan; Sanders, Jeremy K M.

In: Angewandte Chemie-International Edition, Vol. 51, No. 6, 06.02.2012, p. 1443-1447.

Research output: Contribution to journalArticle

Cougnon, FBL, Jenkins, NA, Pantoș, GD & Sanders, JKM 2012, 'Templated dynamic synthesis of a [3]catenane' Angewandte Chemie-International Edition, vol. 51, no. 6, pp. 1443-1447. DOI: 10.1002/anie.201106885
Cougnon FBL, Jenkins NA, Pantoș GD, Sanders JKM. Templated dynamic synthesis of a [3]catenane. Angewandte Chemie-International Edition. 2012 Feb 6;51(6):1443-1447. Available from, DOI: 10.1002/anie.201106885
Cougnon, Fabien B L ; Jenkins, Nicholas A ; Pantoș, G Dan ; Sanders, Jeremy K M. / Templated dynamic synthesis of a [3]catenane. In: Angewandte Chemie-International Edition. 2012 ; Vol. 51, No. 6. pp. 1443-1447
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