@article{955c182a15214c4aa7651a511daebfd6,
title = "Targeted delivery of maytansine to liver cancer cells via galactose-modified supramolecular two-dimensional glycomaterial",
abstract = "A two-dimensional (2D) glycomaterial for targeted delivery of maytansine to liver cancer cells was developed. Host-guest interaction between a galactosyl dye and human serum albumin (HSA) produces supramolecular galactoside-HSA conjugates, which are then used to coat 2D MoS2. The 2D glycomaterial was shown to be capable of the targeted delivery of maytansine to a liver cancer cell line that highly expresses a galactose receptor, resulting in greater cytotoxicity than maytansine alone.",
author = "Xie, {Hai Na} and Chen, {Yu Yuan} and Zhu, {Guo Biao} and Han, {Hai Hao} and Hu, {Xi Le} and Pan, {Zhi Qiang} and Yi Zang and Xie, {Dong Hao} and He, {Xiao Peng} and Jia Li and James, {Tony D.}",
note = "X.-P. H. thanks the National Natural Science Foundation of China (No. 21788102, 91853201), the Shanghai Science and Technology Committee (No. 19410712600), the Shanghai Municipal Science and Technology Major Project (No. 2018SHZDZX03), the Fundamental Research Funds for the Central Universities (222201717003) and the Programme of Introducing Talents of Discipline to Universities (B16017) for financial support. H.-H. H. thanks the National Natural Science Foundation of China (No. 22107029) and Project funded by China Postdoctoral Science Foundation (No. 2020M681196). T. D. J. wishes to thank the Royal Society for a Wolfson Research Merit Award and the Open Research Fund of the School of Chemistry and Chemical Engineering, Henan Normal University for support (2020ZD01).",
year = "2022",
month = apr,
day = "5",
doi = "10.1039/d1cc06809a",
language = "English",
volume = "58",
pages = "5029--5032",
journal = "Chemical communications (Cambridge, England)",
issn = "1359-7345",
publisher = "Royal Society of Chemistry",
}
