Michael David Threadgill (Inventor), Matthew David Lloyd (Inventor), Andrew Spencer Thompson (Inventor), Amit Nathubhai (Inventor), Pauline Joy Wood (Inventor), Helen Angharad Paine (Inventor), Ekaterina Kumpan (Inventor), Peter Thomas Sunderland (Inventor), Esther Chue Yen Woon (Inventor)

Research output: Patent


The present invention relates to a compound of formula I wherein X is C(R6) or N, Y is C or N, and ring A, ring B, R1 and R2 have the meanings defined herein, provided that when ring B is carbocyclic, X is C(R6); or a pharmaceutically acceptable salt or solvate thereof. The compounds are tankyrase-1 and tankyrase-2 inhibitors and are useful in the treatment of a number of conditions, including cancer.

Original languageEnglish
Patent numberWO2014087165
Priority date6/12/12
Publication statusPublished - 12 Jun 2014


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