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Tandem transformation of glycerol via microbial fermentation and enzymatic esterification is presented. The reaction can be performed with purified waste glycerol from biodiesel production in a continuous mode, combining continuous fermentation with membrane-supported enzymatic esterification. Continuous anaerobic fermentation was optimized resulting in the productivity of 2.4 g L -1 h -1 of 1,3-propanediol. Biphasic esterification of 1,3-propanediol was optimized to achieve ester yield of up to 75%. A hollow fibre membrane contactor with immobilized Rhizomucor miehei lipase was demonstrated for the continuous tandem fermentation-esterification process.
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- 1 Finished
ENGINEERING THE CONVERGENCE OF CHEMISTRY AND BIOLOGY: RESOL VING THE INCOMPATIBILITY OF BIO- AND CHEMICAL CATALYSIS
Lapkin, A. & Davidson, M.
2/10/06 → 30/08/09
Project: Research council