Synthetic Access to Ring-Expanded N-Heterocyclic Carbene (RE-NHC) Copper Complexes and their Performance in Click Chemistry

Jonathan W. Hall, Damien Bouchet, Mary F. Mahon, Michael K. Whittlesey, Catherine S.J. Cazin

Research output: Contribution to journalArticlepeer-review

Abstract

The facile syntheses of ring-expanded N-heterocyclic carbene (RE-NHC) copper(I) halide complexes are reported. The method makes use of a weak inorganic base in a green solvent. The reaction times can be greatly reduced by use of this weak-base route under microwave irradiation. The easy access to these complexes permits an evaluation of the catalytic activity and reaction profiling of [Cu(RE-NHC)X] complexes in the Huisgen 1,3-cycloaddition reaction.

Original languageEnglish
Pages (from-to)1252-1261
Number of pages10
JournalOrganometallics
Volume40
Issue number9
Early online date27 Apr 2021
DOIs
Publication statusPublished - 10 May 2021

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Organic Chemistry
  • Inorganic Chemistry

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