Abstract
Cyrene as a bio-alternative solvent: a highly efficient, waste minimizing protocol for the synthesis of ureas from isocyanates and secondary amines in the bio-available solvent Cyrene is reported. This method eliminated the use of toxic solvents, such as DMF, and established a simple work-up procedure for removal of the Cyrene, which led to a 28-fold increase in molar efficiency vs. industrial std. protocols. [on SciFinder(R)]
| Original language | English |
|---|---|
| Pages (from-to) | 2123-2128 |
| Number of pages | 6 |
| Journal | Green Chemistry |
| Volume | 19 |
| Issue number | 9 |
| Early online date | 24 Apr 2017 |
| DOIs | |
| Publication status | Published - 7 May 2017 |
Keywords
- isocyanate secondary amine coupling cyrene
- arylurea prepn