Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation

S J Pridmore; P A Slatford; J E Taylor; M K Whittlesey; J M J Williams

doi:10.1016/j.tet.2009.06.108

Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation

S J Pridmore, P A Slatford, J E Taylor, M K Whittlesey, J M J Williams

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

53 Citations (SciVal)

Abstract

Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)(3)(CO)H-2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. (C) 2009 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	8981-8986
Number of pages	6
Journal	Tetrahedron
Volume	65
Issue number	44
DOIs	https://doi.org/10.1016/j.tet.2009.06.108
Publication status	Published - 2009

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10.1016/j.tet.2009.06.108

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abstract = "Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)(3)(CO)H-2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. (C) 2009 Elsevier Ltd. All rights reserved.",

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AU - Pridmore, S J

AU - Slatford, P A

AU - Taylor, J E

AU - Whittlesey, M K

AU - Williams, J M J

PY - 2009

Y1 - 2009

N2 - Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)(3)(CO)H-2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. (C) 2009 Elsevier Ltd. All rights reserved.

AB - Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)(3)(CO)H-2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. (C) 2009 Elsevier Ltd. All rights reserved.

UR - https://www.scopus.com/pages/publications/70349318368

UR - http://dx.doi.org/10.1016/j.tet.2009.06.108

U2 - 10.1016/j.tet.2009.06.108

DO - 10.1016/j.tet.2009.06.108

M3 - Article

SN - 0040-4020

VL - 65

SP - 8981

EP - 8986

JO - Tetrahedron

JF - Tetrahedron

IS - 44

ER -

Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation

Abstract

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